C₆H₅CH₂CHNC₂H₅COCH₃N₂CH₂SC₆H₅

Base Information

• Chemical Name: C₆H₅CH₂CHNC₂H₅COCH₃N₂CH₂SC₆H₅
• CAS No.: 1027165-81-6
• Molecular Formula: C₁₉H₂₃N₃OS
• Molecular Weight: 341.477
• Mol file: 1027165-81-6.mol

Synonyms:C₆H₅CH₂CHNC₂H₅COCH₃N₂CH₂SC₆H₅

Chemical Property of C₆H₅CH₂CHNC₂H₅COCH₃N₂CH₂SC₆H₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₆H₅CH₂CHNC₂H₅COCH₃N₂CH₂SC₆H₅

There total 1 articles about C₆H₅CH₂CHNC₂H₅COCH₃N₂CH₂SC₆H₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

azidomethyl phenyl sulphide (77422-70-9) + ethylmagnesium chloride (2386-64-3) + acetic anhydride (108-24-7) + (R,R)-p-Chlorophenyl-1-chloro-2-phenylethyl sulfoxide (222016-68-4) → C6H5CH2CHNC2H5COCH3N2CH2SC6H5 (1027165-81-6)

Guidance literature:

ethylmagnesium chloride; (R,R)-p-Chlorophenyl-1-chloro-2-phenylethyl sulfoxide; In tetrahydrofuran; at -78 - -30 ℃; for 1.5h;

azidomethyl phenyl sulphide; In tetrahydrofuran; at -78 ℃; for 1h;

acetic anhydride; In tetrahydrofuran; at -30 ℃; for 1h; Further stages.;

DOI:10.1021/ol0160248

Reference yield:

C6H5CH2CHNC2H5COCH3N2CH2SC6H5 (1027165-81-6) → (N)-(1-phenyl-2-butyl)acetamide (69622-20-4) + (R)-N-(1-phenylbutan-2-yl)acetamide

Guidance literature:

With potassium hydroxide; In dimethyl sulfoxide; at 0 - 20 ℃; Title compound not separated from byproducts.;

DOI:10.1021/ol0160248

Reference yield:

C6H5CH2CHNC2H5COCH3N2CH2SC6H5 (1027165-81-6) → S-(+)-1-phenyl-2-aminobutane hydrochloride (87923-46-4)

Guidance literature:

Multi-step reaction with 2 steps

1: KOH / dimethylsulfoxide / 0 - 20 °C

2: aq. HCl / 0.5 h / 20 °C

With hydrogenchloride; potassium hydroxide; In dimethyl sulfoxide;

DOI:10.1021/ol0160248

upstream raw materials:

azidomethyl phenyl sulphide

ethylmagnesium chloride

acetic anhydride

(R,R)-p-Chlorophenyl-1-chloro-2-phenylethyl sulfoxide

Downstream raw materials:

(N)-(1-phenyl-2-butyl)acetamide

S-(+)-1-phenyl-2-aminobutane hydrochloride