C₂₄H₂₉NO₆

Base Information

• Chemical Name: C₂₄H₂₉NO₆
• CAS No.: 1263815-51-5
• Molecular Formula: C₂₄H₂₉NO₆
• Molecular Weight: 427.497
• Mol file: 1263815-51-5.mol

Synonyms:C₂₄H₂₉NO₆

Chemical Property of C₂₄H₂₉NO₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₂₉NO₆

There total 6 articles about C₂₄H₂₉NO₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cis-1-phenyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid methyl ester + di-tert-butyl dicarbonate (24424-99-5) → C24H29NO6 (1263815-51-5)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 16h;

DOI:10.1016/j.ejmech.2010.11.025

Reference yield:

levodopa (59-92-7,90638-38-3) → C24H29NO6 (1263815-51-5)

Guidance literature:

Multi-step reaction with 6 steps

1: thionyl chloride / 72 h / 20 °C

2: sodium acetate; acetic acid / 20 h / 20 °C

3: sodium formate; acetic anhydride / 4 h / 20 °C

4: potassium carbonate / acetone / 10 h / Reflux

5: hydrogenchloride / methanol / 3 h / Reflux

6: triethylamine / dichloromethane / 16 h / 20 °C

With hydrogenchloride; thionyl chloride; sodium formate; sodium acetate; acetic anhydride; potassium carbonate; acetic acid; triethylamine; In methanol; dichloromethane; acetone; 2: |Pictet-Spengler Synthesis;

DOI:10.1016/j.cclet.2013.02.014

Reference yield:

C17H17NO4 (1173933-70-4) → C24H29NO6 (1263815-51-5)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium formate; acetic anhydride / 4 h / 20 °C

2: potassium carbonate / acetone / 10 h / Reflux

3: hydrogenchloride / methanol / 3 h / Reflux

4: triethylamine / dichloromethane / 16 h / 20 °C

With hydrogenchloride; sodium formate; acetic anhydride; potassium carbonate; triethylamine; In methanol; dichloromethane; acetone;

DOI:10.1016/j.cclet.2013.02.014

upstream raw materials:

di-tert-butyl dicarbonate

levodopa

C₁₇H₁₇NO₄

L-DOPA methyl ester

Downstream raw materials:

C₂₃H₂₇NO₅

C₅₂H₇₀N₄O₈

C₅₃H₇₂N₄O₈

C₅₄H₇₄N₄O₈

Refernces

• 1、 Xu, Geng,Yan, Zheng,Wang, Nan,Liu, Zhanzhu. "Synthesis and cytotoxicity of cis-dichloroplatinum (II) complexes of (1S,3S)-1,2,3,4-tetrahydroisoquinolines". experimental part. p. 356 - 363. Retrieved 2011/02/26.