2-(3-hydroxypropyl)-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione

Base Information

• Chemical Name: 2-(3-hydroxypropyl)-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione
• CAS No.: 40740-33-8
• Molecular Formula: C₁₂H₁₆O₃
• Molecular Weight: 208.257
• Mol file: 40740-33-8.mol

Synonyms:2-(3-hydroxypropyl)-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione

Chemical Property of 2-(3-hydroxypropyl)-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(3-hydroxypropyl)-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione

There total 25 articles about 2-(3-hydroxypropyl)-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-<3-(tert-butyldimethylsilyloxy)propyl>-3,3,6,6-tetramethoxy-2,4,5-trimethyl-1,4-cyclohexadiene → 2-(3-hydroxypropyl)-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione (40740-33-8)

Guidance literature:

With hydrogenchloride; In acetone; for 4h; Ambient temperature;

Reference yield: 78.0%

1,4-dimethoxy-2-(3-hydroxypropyl)-3,5,6-trimethylbenzene (87541-83-1) → 2-(3-hydroxypropyl)-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione (40740-33-8)

Guidance literature:

With ammonium cerium (IV) nitrate; In tetrahydrofuran; water; at 0 - 20 ℃; for 2h;

Reference yield: 41.2%

dimethyl esther of 2-(2,5-dimethoxy-3,4,6-trimethylphenylmethyl)malonic acid (144707-04-0) → 2-(3-hydroxypropyl)-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione (40740-33-8)

Guidance literature:

With boron tribromide; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1007/BF00473932

upstream raw materials:

(E)-6-(2-ethoxycarbonylvinyl)-2,3,5-trimethyl-1,4-benzoquinone

dimethyl esther of 2-(2,5-dimethoxy-3,4,6-trimethylphenylmethyl)malonic acid

2,3,5-trimethyl-6-(3'-hydroxypropyl)-hydroquinone

4-Benzenesulfinyl-2-(3-hydroxy-propyl)-3,5,6-trimethyl-phenol

Downstream raw materials:

2,7,12,18-tetramethyl-3-vinyl-8-ethyl-13²-methoxycarbonyl-17-<2-<3-(3,5,6-trimethyl-p-benzoquinonyl)propoxycarbonyl>ethyl>phorbine

C₆₀H₇₀N₄O₁₀