3-(benzylamino)-5-((3-carbamoyl-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)benzoic acid

Base Information

Chemical Name:3-(benzylamino)-5-((3-carbamoyl-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)benzoic acid
CAS No.:1445787-89-2
Molecular Formula:C₃₀H₂₆N₆O₅
Molecular Weight:550.574
Hs Code.:

Synonyms:3-(benzylamino)-5-((3-carbamoyl-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)benzoic acid

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Chemical Property of 3-(benzylamino)-5-((3-carbamoyl-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)benzoic acid

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Technology Process of 3-(benzylamino)-5-((3-carbamoyl-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)benzoic acid

There total 6 articles about 3-(benzylamino)-5-((3-carbamoyl-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.5%

: methy 3-(benzylamino)-5-((3-carbamoyl-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)benzoate trifluoroacetic acid salt

: 1445787-89-2
3-(benzylamino)-5-((3-carbamoyl-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)benzoic acid

Guidance literature:: With sodium hydroxide; In methanol; at 20 ℃;

Reference yield:

: 100-39-0
benzyl bromide

: 1445787-89-2
3-(benzylamino)-5-((3-carbamoyl-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)benzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: N,N-dimethyl-formamide / 0.33 h / 120 °C / Microwave irradiation

2: hydrogen; acetic acid; platinum(IV) oxide / 2 h / 20 °C

3: sodium hydroxide / methanol / 20 °C

With platinum(IV) oxide; hydrogen; acetic acid; sodium hydroxide; In methanol; N,N-dimethyl-formamide;

Reference yield:

: 23218-93-1
3-amino-5-nitro-benzoic acid methyl ester

: 1445787-89-2
3-(benzylamino)-5-((3-carbamoyl-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)benzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: N,N-dimethyl-formamide / 0.33 h / 120 °C / Microwave irradiation

2: hydrogen; acetic acid; platinum(IV) oxide / 2 h / 20 °C

3: sodium hydroxide / methanol / 20 °C

With platinum(IV) oxide; hydrogen; acetic acid; sodium hydroxide; In methanol; N,N-dimethyl-formamide;