trans-4-(4-Cyanophenyl)cyclohexylacetaldehyde

Base Information

Chemical Name:trans-4-(4-Cyanophenyl)cyclohexylacetaldehyde
CAS No.:96184-94-0
Molecular Formula:C₁₅H₁₇NO
Molecular Weight:227.306
Hs Code.:
European Community (EC) Number:619-201-5
DSSTox Substance ID:DTXSID501224828

Synonyms:trans-4-(4-cyanophenyl)cyclohexylacetaldehyde;SCHEMBL8835117;SCHEMBL9457797;PCPICPGMEBRTKB-MQMHXKEQSA-N;PCPICPGMEBRTKB-UHFFFAOYSA-N;DTXSID501224828;96184-94-0;2-(4-(4-cyanophenyl)cyclohexyl)acetaldehyde;[trans-4-(p-cyanophenyl)cyclohexyl]acetaldehyde;[trans-4-(p-cyanophenyl)cyclohexyl]-acetaldehyde;2-[trans-4-(p-cyanophenyl)cyclohexyl]acetaldehyde;4-{trans-4'-(formylmethyl)cyclohexyl}benzonitrile;Benzonitrile, 4-[4-(2-oxoethyl)cyclohexyl]-, trans-

Suppliers and Price of trans-4-(4-Cyanophenyl)cyclohexylacetaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of trans-4-(4-Cyanophenyl)cyclohexylacetaldehyde

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:227.131014166
Heavy Atom Count:17
Complexity:287

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC(CCC1CC=O)C2=CC=C(C=C2)C#N

Technology Process of trans-4-(4-Cyanophenyl)cyclohexylacetaldehyde

There total 4 articles about trans-4-(4-Cyanophenyl)cyclohexylacetaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.7%

: 4-{trans-4'-(2-methoxyethenyl)cyclohexyl}benzonitrile

: 96184-94-0
2-[trans-4-(p-cyanophenyl)cyclohexyl]acetaldehyde

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; water;

Reference yield:

: 95925-52-3
p-[4-(methoxymethylene)cyclohexyl]benzonitrile

: 96184-94-0
2-[trans-4-(p-cyanophenyl)cyclohexyl]acetaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 29 percent / 2N HCl / tetrahydrofuran / 0.5 h / Heating

2: 1.) t-BuOK; 2.) 2N HCl / 1.) t-butyl methyl ether, -10 deg C - RT, 165 min; 2.) THF, reflux, 30 min

With hydrogenchloride; potassium tert-butylate; In tetrahydrofuran;

Reference yield:

: 73204-07-6
4-(4-cyanophenyl)cyclohexanone

: 96184-94-0
2-[trans-4-(p-cyanophenyl)cyclohexyl]acetaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: 94 percent / t-BuOK / various solvent(s); tetrahydrofuran / 2.75 h / -10 - 25 °C

2: 29 percent / 2N HCl / tetrahydrofuran / 0.5 h / Heating

3: 1.) t-BuOK; 2.) 2N HCl / 1.) t-butyl methyl ether, -10 deg C - RT, 165 min; 2.) THF, reflux, 30 min

With hydrogenchloride; potassium tert-butylate; In tetrahydrofuran;