1-bromo-3-(4-ethylbenzyl)-2-methyl-5-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos-1-yl)-benzene

Base Information

Chemical Name:1-bromo-3-(4-ethylbenzyl)-2-methyl-5-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos-1-yl)-benzene
CAS No.:1022983-88-5
Molecular Formula:C₃₀H₃₅BrO₉
Molecular Weight:619.506
Hs Code.:

Synonyms:1-bromo-3-(4-ethylbenzyl)-2-methyl-5-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos-1-yl)-benzene

Suppliers and Price of 1-bromo-3-(4-ethylbenzyl)-2-methyl-5-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos-1-yl)-benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-bromo-3-(4-ethylbenzyl)-2-methyl-5-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos-1-yl)-benzene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-bromo-3-(4-ethylbenzyl)-2-methyl-5-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos-1-yl)-benzene

There total 8 articles about 1-bromo-3-(4-ethylbenzyl)-2-methyl-5-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos-1-yl)-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 1050200-97-9
1-bromo-3-(4-ethylbenzyl)-5-(1-methoxy-D-glucopyranos-1-yl)-2-methyl-benzene

: 108-24-7
acetic anhydride

: 1022983-88-5
1-bromo-3-(4-ethylbenzyl)-2-methyl-5-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos-1-yl)-benzene

Guidance literature:: 1-bromo-3-(4-ethylbenzyl)-5-(1-methoxy-D-glucopyranos-1-yl)-2-methyl-benzene; With triethylsilane; boron trifluoride diethyl etherate; In dichloromethane; acetonitrile; at -15 - 0 ℃; for 0.5h;

acetic anhydride; With pyridine; dmap; In dichloromethane; at 0 - 20 ℃; for 1h;

Reference yield:

: C₂₂H₂₇BrO₅

: 108-24-7
acetic anhydride

: 1022983-88-5
1-bromo-3-(4-ethylbenzyl)-2-methyl-5-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos-1-yl)-benzene

Guidance literature:: With pyridine; dmap; In dichloromethane; at 0 - 20 ℃; for 1h; Cooling with ice;

Reference yield:

: 76006-33-2
3-bromo-2-methylbenzoic acid

: 1022983-88-5
1-bromo-3-(4-ethylbenzyl)-2-methyl-5-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos-1-yl)-benzene

Guidance literature:: Multi-step reaction with 6 steps

1.1: N-iodo-succinimide; sulfuric acid / 5 - 20 °C

2.1: thionyl chloride / N,N-dimethyl-formamide / 1 h / Heating / reflux

3.1: aluminum (III) chloride / dichloromethane / 2 h / 0 - 20 °C

4.1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane; acetonitrile / 14.05 h / 0 - 20 °C

5.1: TurboGrignard / tetrahydrofuran / 1 h / -60 - -20 °C

5.2: 6 h / -20 - -5 °C

5.3: 6 h / 40 °C

6.1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane; acetonitrile / 0.5 h / -15 - 0 °C

6.2: 1 h / 0 - 20 °C

With triethylsilane; aluminum (III) chloride; N-iodo-succinimide; TurboGrignard; thionyl chloride; sulfuric acid; boron trifluoride diethyl etherate; N,N-dimethyl-formamide; In tetrahydrofuran; dichloromethane; acetonitrile;