(E)-4,4'-(6-(2-((1-(4-fluorobenzyl)-1H-indol-3-yl)methylene)hydrazinyl)pyrimidine-2,4-diyl)dimorpholine

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Chemical Name:(E)-4,4'-(6-(2-((1-(4-fluorobenzyl)-1H-indol-3-yl)methylene)hydrazinyl)pyrimidine-2,4-diyl)dimorpholine
CAS No.:1399879-64-1
Molecular Formula:C₂₈H₃₀FN₇O₂
Molecular Weight:515.59
Hs Code.:

Synonyms:(E)-4,4'-(6-(2-((1-(4-fluorobenzyl)-1H-indol-3-yl)methylene)hydrazinyl)pyrimidine-2,4-diyl)dimorpholine

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Chemical Property of (E)-4,4'-(6-(2-((1-(4-fluorobenzyl)-1H-indol-3-yl)methylene)hydrazinyl)pyrimidine-2,4-diyl)dimorpholine

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Technology Process of (E)-4,4'-(6-(2-((1-(4-fluorobenzyl)-1H-indol-3-yl)methylene)hydrazinyl)pyrimidine-2,4-diyl)dimorpholine

There total 2 articles about (E)-4,4'-(6-(2-((1-(4-fluorobenzyl)-1H-indol-3-yl)methylene)hydrazinyl)pyrimidine-2,4-diyl)dimorpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 299907-60-1
4,4'-(6-hydrazinylpyrimidine-2,4-diyl)dimorpholine

: 192997-23-2
1?(4?fluorobenzyl)?1H?indole?3?carbaldehyde

: 1399879-64-1
(E)-4,4'-(6-(2-((1-(4-fluorobenzyl)-1H-indol-3-yl)methylene)hydrazinyl)pyrimidine-2,4-diyl)dimorpholine

Guidance literature:: With acetic acid; In ethanol; Reflux;
DOI:10.1002/ardp.201200074

Reference yield:

: 10244-24-3
2,4-[bis(morpholino)]-6-chloropyrimidine

: 1399879-64-1
(E)-4,4'-(6-(2-((1-(4-fluorobenzyl)-1H-indol-3-yl)methylene)hydrazinyl)pyrimidine-2,4-diyl)dimorpholine

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / water / 80 °C

2: acetic acid / ethanol / Reflux

With hydrazine hydrate; acetic acid; In ethanol; water;
DOI:10.1002/ardp.201200074