(2S,3R)-trans-(4-methoxyphenyl)glycidic acid

Base Information

Chemical Name:(2S,3R)-trans-(4-methoxyphenyl)glycidic acid
CAS No.:106003-21-8
Molecular Formula:C₁₀H₁₀O₄
Molecular Weight:194.187
Hs Code.:

Synonyms:(2S,3R)-trans-(4-methoxyphenyl)glycidic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2S,3R)-trans-(4-methoxyphenyl)glycidic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (2S,3R)-trans-(4-methoxyphenyl)glycidic acid

There total 3 articles about (2S,3R)-trans-(4-methoxyphenyl)glycidic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 96125-49-4
methyl trans-3-(4-methoxyphenyl)glycidate

: 5703-26-4
4-Methoxyphenylacetaldehyde

: 105560-93-8
methyl (2R,3S)-3-(4-methoxyphenyl)glycidate

: 106003-21-8
(2S,3R)-trans-(4-methoxyphenyl)glycidic acid

Guidance literature:: In cyclohexane; water; for 1.5h; Ambient temperature; enzymatic hydrolysis by lipase from Candida cylindracea (CCL), pH 7.4, other enzymes; enzymatic transesterification;
DOI:10.1021/jo00050a049

Reference yield:

: 42245-42-1
methyl 3-(4-methoxyphenyl)glycidate

: 105560-93-8
methyl (2R,3S)-3-(4-methoxyphenyl)glycidate

: 106003-21-8
(2S,3R)-trans-(4-methoxyphenyl)glycidic acid

Guidance literature:: With water; In acetone; at 25 ℃; Rhizopus arrhizus mycelium lipase, pH 7;

Reference yield:

: 96125-49-4
methyl trans-3-(4-methoxyphenyl)glycidate

: 105560-93-8
methyl (2R,3S)-3-(4-methoxyphenyl)glycidate

: 106003-21-8
(2S,3R)-trans-(4-methoxyphenyl)glycidic acid

Guidance literature:: With water; In toluene; at 20 ℃; for 72h; optical yield given as %ee; enantioselective reaction; Enzymatic reaction;
DOI:10.1016/j.tetasy.2009.11.012