{[(2R,4S,6R)-4-(benzyloxy)-6-methyl-tetrahydro-2H-pyran-2-yl]methoxy}(tert-butyl)dimethylsilane

Base Information

Chemical Name:{[(2R,4S,6R)-4-(benzyloxy)-6-methyl-tetrahydro-2H-pyran-2-yl]methoxy}(tert-butyl)dimethylsilane
CAS No.:1206548-36-8
Molecular Formula:C₂₀H₃₄O₃Si
Molecular Weight:350.574
Hs Code.:

Synonyms:{[(2R,4S,6R)-4-(benzyloxy)-6-methyl-tetrahydro-2H-pyran-2-yl]methoxy}(tert-butyl)dimethylsilane

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Chemical Property of {[(2R,4S,6R)-4-(benzyloxy)-6-methyl-tetrahydro-2H-pyran-2-yl]methoxy}(tert-butyl)dimethylsilane

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Technology Process of {[(2R,4S,6R)-4-(benzyloxy)-6-methyl-tetrahydro-2H-pyran-2-yl]methoxy}(tert-butyl)dimethylsilane

There total 1 articles about {[(2R,4S,6R)-4-(benzyloxy)-6-methyl-tetrahydro-2H-pyran-2-yl]methoxy}(tert-butyl)dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1206548-33-5
[(2R,4S,6R)-2-(tert-butyldimethylsilyloxy)methyl]-6-methyl-tetrahydro-2H-pyran-4-ol

: 100-39-0
benzyl bromide

: 1206548-36-8
{[(2R,4S,6R)-4-(benzyloxy)-6-methyl-tetrahydro-2H-pyran-2-yl]methoxy}(tert-butyl)dimethylsilane

Guidance literature:: [(2R,4S,6R)-2-(tert-butyldimethylsilyloxy)methyl]-6-methyl-tetrahydro-2H-pyran-4-ol; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.5h;

benzyl bromide; In tetrahydrofuran; at 0 - 20 ℃; for 2h;
DOI:10.1016/j.tet.2009.10.100