(Z)-3-(benzofuran-2-yl)-2-(3,4-dimethoxyphenyl)acrylonitrile

Base Information

• Chemical Name: (Z)-3-(benzofuran-2-yl)-2-(3,4-dimethoxyphenyl)acrylonitrile
• CAS No.: 912288-40-5
• Molecular Formula: C₁₉H₁₅NO₃
• Molecular Weight: 305.333
• Mol file: 912288-40-5.mol

Synonyms:(Z)-3-(benzofuran-2-yl)-2-(3,4-dimethoxyphenyl)acrylonitrile

Chemical Property of (Z)-3-(benzofuran-2-yl)-2-(3,4-dimethoxyphenyl)acrylonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-3-(benzofuran-2-yl)-2-(3,4-dimethoxyphenyl)acrylonitrile

There total 2 articles about (Z)-3-(benzofuran-2-yl)-2-(3,4-dimethoxyphenyl)acrylonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.7%

→ (Z)-3-(benzofuran-2-yl)-2-(3,4-dimethoxyphenyl)acrylonitrile (912288-40-5)

Guidance literature:

Reference yield:

3,4-dimethoxyphenylacetonitrile (93-17-4) + 2-formylbenzo[b]furan (4265-16-1) → (Z)-3-(benzofuran-2-yl)-2-(3,4-dimethoxyphenyl)acrylonitrile (912288-40-5)

Guidance literature:

With sodium methylate; In methanol; Reflux;

DOI:10.1016/j.ejmech.2014.12.050

Reference yield:

(Z)-3-(benzofuran-2-yl)-2-(3,4-dimethoxyphenyl)acrylonitrile (912288-40-5) + azido tributyltin (IV) (17846-68-3) → C31H42N4O3Sn

Guidance literature:

In o-xylene; N,N-dimethyl-formamide; at 100 ℃; for 36h;

DOI:10.1016/j.tetlet.2016.03.040

upstream raw materials:

3,4-dimethoxyphenylacetonitrile

2-formylbenzo[b]furan