1-phenethyl-4-piperidine

Base Information

Chemical Name:1-phenethyl-4-piperidine
CAS No.:117523-87-2
Molecular Formula:C₁₉H₂₅N₃
Molecular Weight:295.428
Hs Code.:

1-phenethyl-4-<N-(4-methylpyridin-2-yl)amino>piperidine

Synonyms:1-phenethyl-4-piperidine

Suppliers and Price of 1-phenethyl-4-piperidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-phenethyl-4-piperidine

Chemical Property:

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Technology Process of 1-phenethyl-4-piperidine

There total 5 articles about 1-phenethyl-4-piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 117523-86-1
(4-Methyl-1-oxy-pyridin-2-yl)-(1-phenethyl-piperidin-4-yl)-amine

: 117523-87-2
1-phenethyl-4-piperidine

Guidance literature:: With phosphorus trichloride; In chloroform; for 2h; Heating;
DOI:10.1021/jm00123a028

Reference yield:

: 3678-62-4
2-chloro-4-picoline

: 117523-87-2
1-phenethyl-4-piperidine

Guidance literature:: Multi-step reaction with 3 steps

1: 35 percent / 3-chloroperoxybenzoic acid / CHCl₃ / 4 h / Heating

2: 26 percent / Na₂CO₃, KI / 3-methyl-butan-1-ol / 48 h / Heating

3: 61 percent / PCl₃ / CHCl₃ / 2 h / Heating

With sodium carbonate; 3-chloro-benzenecarboperoxoic acid; potassium iodide; phosphorus trichloride; In i-Amyl alcohol; chloroform;
DOI:10.1021/jm00123a028

Reference yield:

: 52313-61-8
2-chloro-4-methylpyridin-N-oxide

: 117523-87-2
1-phenethyl-4-piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: 26 percent / Na₂CO₃, KI / 3-methyl-butan-1-ol / 48 h / Heating

2: 61 percent / PCl₃ / CHCl₃ / 2 h / Heating

With sodium carbonate; potassium iodide; phosphorus trichloride; In i-Amyl alcohol; chloroform;
DOI:10.1021/jm00123a028