Technology Process of C12H18FN
There total 2 articles about C12H18FN which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 48 h / 20 °C / Cooling with ice
2: ammonium hydroxide; hydrogen / ethanol / 20 h / 20 °C
With
ammonium hydroxide; hydrogen; sodium hydride;
In
ethanol; N,N-dimethyl-formamide; mineral oil;
DOI:10.1016/j.bmc.2011.07.030
- Guidance literature:
-
Multi-step reaction with 3 steps
1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 72 h / 20 °C / Cooling with ice
2: hydrogenchloride / ethyl acetate / 18 h / 20 °C / Cooling with ice
3: sodium hydrogencarbonate / dichloromethane; water / 0.25 h / 20 °C / Saturated solution
With
hydrogenchloride; sodium hydrogencarbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2011.07.030