Technology Process of C13H18O2
There total 3 articles about C13H18O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
Oxone; Shi's ketone; tetra(n-butyl)ammonium hydrogensulfate; edetate disodium; potassium carbonate; acetic acid; potassium hydroxide;
In
Dimethoxymethane; acetonitrile;
at -10 ℃;
for 3h;
optical yield given as %ee;
Inert atmosphere;
aq. buffer;
DOI:10.1021/ja201467z
- Guidance literature:
-
With
oxone; C28H42O7; tetra(n-butyl)ammonium hydrogensulfate; sodium hydrogencarbonate;
In
water; acetonitrile;
at 0 ℃;
for 24h;
pH=7 - 7.5;
optical yield given as %ee;
enantioselective reaction;
aq. buffer;
DOI:10.1016/j.tetasy.2009.02.039
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydride / tetrahydrofuran / 0.17 h / 0 °C / Inert atmosphere
1.2: 12 h / 0 - 70 °C / Inert atmosphere
2.1: Oxone; Shi's ketone; tetra(n-butyl)ammonium hydrogensulfate; edetate disodium; potassium carbonate; acetic acid; potassium hydroxide / Dimethoxymethane; acetonitrile / 3 h / -10 °C / Inert atmosphere; aq. buffer
With
Oxone; Shi's ketone; tetra(n-butyl)ammonium hydrogensulfate; edetate disodium; sodium hydride; potassium carbonate; acetic acid; potassium hydroxide;
In
tetrahydrofuran; Dimethoxymethane; acetonitrile;
DOI:10.1021/ja201467z
