4-Chloro-8-methylquinazoline

Base Information

Chemical Name:4-Chloro-8-methylquinazoline
CAS No.:58421-80-0
Molecular Formula:C9H7ClN2
Molecular Weight:178.621
Hs Code.:2933990090
European Community (EC) Number:835-208-8
DSSTox Substance ID:DTXSID50592667
Wikidata:Q72455113
Mol file:58421-80-0.mol

Synonyms:4-Chloro-8-methylquinazoline;58421-80-0;MFCD08457971;Quinazoline, 4-chloro-8-methyl-;4-CHLORO-8-METHYL-QUINAZOLINE;8-methyl 4 chloro quinazoline;SCHEMBL3763540;DTXSID50592667;UTBDPFFXKANFFT-UHFFFAOYSA-N;BCP18106;AKOS012384449;CS-W001047;DS-6744;4-Chloro-8-methylquinazoline, AldrichCPR;SY045902;DB-015935;EN300-67878;A831875;Z1082217316

Suppliers and Price of 4-Chloro-8-methylquinazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Chloro-8-methylquinazoline
100mg
$ 45.00

TRC
4-Chloro-8-methylquinazoline
500mg
$ 200.00

TRC
4-Chloro-8-methylquinazoline
1g
$ 285.00

SynQuest Laboratories
4-Chloro-8-methylquinazoline 97%
1 g
$ 296.00

SynQuest Laboratories
4-Chloro-8-methylquinazoline 97%
5 g
$ 888.00

Matrix Scientific
4-Chloro-8-methylquinazoline 97%
1g
$ 488.00

Crysdot
4-Chloro-8-methylquinazoline 97%
5g
$ 404.00

ChemScene
4-Chloro-8-methylquinazoline ≥98.0%
1g
$ 117.00

ChemScene
4-Chloro-8-methylquinazoline ≥98.0%
250mg
$ 50.00

ChemScene
4-Chloro-8-methylquinazoline ≥98.0%
5g
$ 318.00

Total 27 raw suppliers

Chemical Property of 4-Chloro-8-methylquinazoline

Chemical Property:

Vapor Pressure:0.00229mmHg at 25°C
Melting Point:129-130 °C
Refractive Index:1.643
Boiling Point:298.2°C at 760 mmHg
PKA:1.06±0.30(Predicted)
Flash Point:162.3°C
PSA：25.78000
Density:1.292
LogP:2.59160
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:178.0297759
Heavy Atom Count:12
Complexity:163

Purity/Quality:

99%, ^*data from raw suppliers

4-Chloro-8-methylquinazoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C2C(=CC=C1)C(=NC=N2)Cl

Technology Process of 4-Chloro-8-methylquinazoline

There total 5 articles about 4-Chloro-8-methylquinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 58421-80-0
4-chloro-8-methylquinazoline

Guidance literature:: With thionyl chloride; N,N-dimethyl-formamide; Reflux;

Reference yield: 86.0%

: 19181-54-5
8-methylquinazolin-4(3H)-one

: 58421-80-0
4-chloro-8-methylquinazoline

Guidance literature:: With trichlorophosphate; at 120 ℃; for 12h; Inert atmosphere;

Reference yield:

: 4389-45-1
3-methylantranilic acid

: 58421-80-0
4-chloro-8-methylquinazoline

Guidance literature:: Multi-step reaction with 2 steps

1: 2 h / 170 °C

2: POCl₃, dimethylaniline / toluene / 4 h / Heating

With 2,3-Dimethylaniline; trichlorophosphate; In toluene;
DOI:10.1016/0968-0896(96)00107-1