alpha-Hexylacrylonitrile

Base Information

• Chemical Name: alpha-Hexylacrylonitrile
• CAS No.: 5633-86-3
• Molecular Formula: C9H15N
• Molecular Weight: 137.22
• Mol file: 5633-86-3.mol

Synonyms:alpha-Hexylacrylonitrile

Chemical Property of alpha-Hexylacrylonitrile

Chemical Property:

• PSA: 23.79000
• LogP: 3.03658

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of alpha-Hexylacrylonitrile

There total 19 articles about alpha-Hexylacrylonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

(E)-2-Bromomethyl-oct-2-enenitrile (333316-79-3) → 2-methyleneoctanenitrile (5633-86-3)

Guidance literature:

(E)-2-Bromomethyl-oct-2-enenitrile; With 1,4-diaza-bicyclo[2.2.2]octane; In tetrahydrofuran; water; at 20 ℃; for 0.25h;

With sodium tetrahydroborate; In tetrahydrofuran; water; at 20 ℃; for 0.25h;

DOI:10.1016/S0040-4039(00)01967-5

Reference yield: 65.0%

n-octyne (629-05-0) + 2-hydroxy-2-methylpropanenitrile (75-86-5) → (E)-non-2-enenitrile (40856-16-4,29127-83-1) + 2-methyleneoctanenitrile (5633-86-3)

Guidance literature:

With (hydridotris(1-pyrazolyl)borato)(1,5-cyclooctadiene)rhodium(I); bis[2-(diphenylphosphino)phenyl] ether; In acetonitrile; at 110 ℃; for 12h; Overall yield = 81 %; stereoselective reaction; Inert atmosphere; Glovebox; Sealed tube;

DOI:10.1021/jacs.7b03749

Reference yield: 61.0%

→ 2-methyleneoctanenitrile (5633-86-3)

Guidance literature:

With bis(acetylacetonate)nickel(II); manganese; 2.9-dimethyl-1,10-phenanthroline; In water; acetonitrile; at 50 ℃; for 24h; Inert atmosphere; Glovebox;

upstream raw materials:

1-cyano-1-methylheptyl acetate

(2-Cyano-2-methoxycarbonyl-octyl)-trimethyl-ammonium; iodide

hydrogen cyanide

n-octyne