8-(4-methoxy-benzenesulfonyl)-3a-phenylselanyl-3,3a,8,8a-tetrahydro-2H-pyrrolo[2,3-b]indole-1,2-dicarboxylic acid dimethyl ester

Base Information

• Chemical Name: 8-(4-methoxy-benzenesulfonyl)-3a-phenylselanyl-3,3a,8,8a-tetrahydro-2H-pyrrolo[2,3-b]indole-1,2-dicarboxylic acid dimethyl ester
• CAS No.: 245756-00-7
• Molecular Formula: C₂₇H₂₆N₂O₇SSe
• Molecular Weight: 601.539
• Mol file: 245756-00-7.mol

Synonyms:8-(4-methoxy-benzenesulfonyl)-3a-phenylselanyl-3,3a,8,8a-tetrahydro-2H-pyrrolo[2,3-b]indole-1,2-dicarboxylic acid dimethyl ester

Chemical Property of 8-(4-methoxy-benzenesulfonyl)-3a-phenylselanyl-3,3a,8,8a-tetrahydro-2H-pyrrolo[2,3-b]indole-1,2-dicarboxylic acid dimethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 8-(4-methoxy-benzenesulfonyl)-3a-phenylselanyl-3,3a,8,8a-tetrahydro-2H-pyrrolo[2,3-b]indole-1,2-dicarboxylic acid dimethyl ester

There total 1 articles about 8-(4-methoxy-benzenesulfonyl)-3a-phenylselanyl-3,3a,8,8a-tetrahydro-2H-pyrrolo[2,3-b]indole-1,2-dicarboxylic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

N-phenylselanylphthalimide (71098-88-9) + 3-[1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-2-methoxycarbonylamino-propionic acid methyl ester → 8-(4-methoxy-benzenesulfonyl)-3a-phenylselanyl-3,3a,8,8a-tetrahydro-2H-pyrrolo[2,3-b]indole-1,2-dicarboxylic acid dimethyl ester (245756-00-7)

Guidance literature:

With toluene-4-sulfonic acid; sodium sulfate; In dichloromethane; at 20 ℃;

DOI:10.1021/jo991093+

Reference yield: 74.0%

8-(4-methoxy-benzenesulfonyl)-3a-phenylselanyl-3,3a,8,8a-tetrahydro-2H-pyrrolo[2,3-b]indole-1,2-dicarboxylic acid dimethyl ester (245756-00-7) → (-)-dimethyl (2S,3aS,8aR)-8-(4-methoxybenzenesulfonyl)-1,2,3,3a,8,8a-hexahydropyrrolo<2,3-b>indole-1,2-dicarboxylate (162302-18-3)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); diphenyl diselenide; tri-n-butyl-tin hydride; In toluene; for 12h; Heating;

DOI:10.1021/jo991093+

Reference yield:

8-(4-methoxy-benzenesulfonyl)-3a-phenylselanyl-3,3a,8,8a-tetrahydro-2H-pyrrolo[2,3-b]indole-1,2-dicarboxylic acid dimethyl ester (245756-00-7) → C27H25(2)HN2O7SSe

Guidance literature:

With tert-butanol-d10; potassium tert-butylate; at 40 ℃; Title compound not separated from byproducts;

DOI:10.1021/jo991093+

upstream raw materials:

N-phenylselanylphthalimide

Downstream raw materials:

(-)-dimethyl (2S,3aS,8aR)-8-(4-methoxybenzenesulfonyl)-1,2,3,3a,8,8a-hexahydropyrrolo<2,3-b>indole-1,2-dicarboxylate