(S*)-2-(2-(dimethylamino)ethyl)-2-(2-fluorophenyl)cyclohexanone

Base Information

• Chemical Name: (S*)-2-(2-(dimethylamino)ethyl)-2-(2-fluorophenyl)cyclohexanone
• CAS No.: 746639-08-7
• Molecular Formula: C₁₆H₂₂FNO
• Molecular Weight: 263.355
• Mol file: 746639-08-7.mol

Synonyms:(S*)-2-(2-(dimethylamino)ethyl)-2-(2-fluorophenyl)cyclohexanone

Chemical Property of (S*)-2-(2-(dimethylamino)ethyl)-2-(2-fluorophenyl)cyclohexanone

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of (S*)-2-(2-(dimethylamino)ethyl)-2-(2-fluorophenyl)cyclohexanone

There total 1 articles about (S*)-2-(2-(dimethylamino)ethyl)-2-(2-fluorophenyl)cyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-amino-3-(2-dimethylaminoethyl)-3-(2-fluorophenyl)cyclohex-1-enecarbonitrile hydrobromide → (S*)-2-(2-(dimethylamino)ethyl)-2-(2-fluorophenyl)cyclohexanone (746639-08-7)

Guidance literature:

With phosphoric acid; acetic acid; In water; for 24h; Heating;

DOI:10.1021/jo040159k

Reference yield:

trimethyl orthoformate (149-73-5) + (S*)-2-(2-(dimethylamino)ethyl)-2-(2-fluorophenyl)cyclohexanone (746639-08-7) → C17H24FNO (1092822-59-7)

Guidance literature:

With sulfuric acid; In methanol; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1021/jm800913d

Reference yield:

(S*)-2-(2-(dimethylamino)ethyl)-2-(2-fluorophenyl)cyclohexanone (746639-08-7) → 6-bromo-2-(2-dimethylaminoethyl)-2-(2-fluorophenyl)cyclohexanone (795261-66-4)

Guidance literature:

With bromine; In chloroform; at 20 ℃; for 1h;

DOI:10.1021/jo040159k

Downstream raw materials:

6-bromo-2-(2-dimethylaminoethyl)-2-(2-fluorophenyl)cyclohexanone

C₁₇H₂₄FNO