methyl 3-{4-[3-(4-chlorophenyl)-2-oxo-5-oxazolidinyl]methoxy}phenylpropionate

Base Information

Chemical Name:methyl 3-{4-[3-(4-chlorophenyl)-2-oxo-5-oxazolidinyl]methoxy}phenylpropionate
CAS No.:154872-47-6
Molecular Formula:C₂₀H₂₀ClNO₅
Molecular Weight:389.835
Hs Code.:

Synonyms:methyl 3-{4-[3-(4-chlorophenyl)-2-oxo-5-oxazolidinyl]methoxy}phenylpropionate

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Chemical Property of methyl 3-{4-[3-(4-chlorophenyl)-2-oxo-5-oxazolidinyl]methoxy}phenylpropionate

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Technology Process of methyl 3-{4-[3-(4-chlorophenyl)-2-oxo-5-oxazolidinyl]methoxy}phenylpropionate

There total 2 articles about methyl 3-{4-[3-(4-chlorophenyl)-2-oxo-5-oxazolidinyl]methoxy}phenylpropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 104-12-1
p-chlorphenylisocyanate

: 81147-94-6,246219-23-8
methyl 3-<4-(2,3-epoxypropoxy)phenyl>propionate

: 154872-47-6
methyl 3-{4-[3-(4-chlorophenyl)-2-oxo-5-oxazolidinyl]methoxy}phenylpropionate

Guidance literature:: With Tributylphosphine oxide; lithium bromide; In xylene; at 140 ℃; for 2h;
DOI:10.1002/ardp.200400920

Reference yield:

: 5597-50-2
3-(4-hydroxyphenyl)propionic acid methyl ester

: 154872-47-6
methyl 3-{4-[3-(4-chlorophenyl)-2-oxo-5-oxazolidinyl]methoxy}phenylpropionate

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / K₂CO₃ / butan-2-one / 8 h / Heating

2: 85 percent / LiBr*H₂O; tri-n-butylphosphine oxide / xylene / 2 h / 140 °C

With Tributylphosphine oxide; potassium carbonate; lithium bromide; In butanone; xylene;
DOI:10.1002/ardp.200400920