2-(Quinoxalin-6-YL)ethanol

Base Information

• Chemical Name: 2-(Quinoxalin-6-YL)ethanol
• CAS No.: 473895-88-4
• Molecular Formula: C₁₀H₁₀N₂O
• Molecular Weight: 174.202
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID00594934
• Wikidata: Q82489864
• Mol file: 473895-88-4.mol

Synonyms:2-(QUINOXALIN-6-YL)ETHANOL;473895-88-4;2-quinoxalin-6-ylethanol;2-(Quinoxalin-6-yl)ethan-1-ol;6-QUINOXALINEETHANOL;SCHEMBL5155836;DTXSID00594934;DA-19246;CS-0452724

Chemical Property of 2-(Quinoxalin-6-YL)ethanol

Chemical Property:

• PSA: 46.01000
• LogP: 1.16460
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 174.079312947
• Heavy Atom Count: 13
• Complexity: 163

Purity/Quality:

98%min ^*data from raw suppliers

2-(quinoxalin-6-yl)ethan-1-ol 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=NC=CN=C2C=C1CCO

Technology Process of 2-(Quinoxalin-6-YL)ethanol

There total 6 articles about 2-(Quinoxalin-6-YL)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-(bromomethyl)quinoxaline (54804-43-2) + 6-hydroxymethyl-quinoxaline (488834-75-9) → 6-Hydroxymethyl-methyl-quinoxaline (473895-88-4)

Guidance literature:

With sodium hydroxide;

Reference yield:

ethyl ester of quinoxalin-6-ylacetic acid (473895-87-3) → 6-Hydroxymethyl-methyl-quinoxaline (473895-88-4)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 20 ℃; for 3.5h;

Reference yield:

6-vinylquinoxaline (874279-33-1) → 6-Hydroxymethyl-methyl-quinoxaline (473895-88-4)

Guidance literature:

6-vinylquinoxaline; With 9-borabicyclo[3.3.1]nonane dimer; In tetrahydrofuran; Heating;

With sodium hydroxide; dihydrogen peroxide; at 20 ℃; Further stages.;

DOI:10.1016/j.bmcl.2007.05.009

upstream raw materials:

6-vinylquinoxaline

6-bromoquinoxaline

ethyl ester of quinoxalin-6-ylacetic acid

2-(bromomethyl)quinoxaline

Downstream raw materials:

C₄₃H₄₀F₄N₆O₅S