54804-43-2Relevant articles and documents
Side chain bromination of mono and dimethyl heteroaromatic and aromatic compounds by solid phase N-bromosuccinimide reaction without radical initiator under microwave
Goswami, Shyamaprosad,Dey, Swapan,Jana, Subrata,Adak, Avijit Kumar
, p. 916 - 917 (2007/10/03)
A series of side chain mono and dibromo derivatives of mono and dimethyl heteroaromatic and aromatic compounds (1-17) were synthesized by one step solid phase N-bromosuccinimide (NBS) reaction without radical initiator by microwave irradiation. The benzylic mono and dibromo products were exclusively preferred except in the case of 6-methylpyridine amides (8 and 9) where nuclear and also side chain bromination resulted. Naphthyridine systems resulted improved yields. By this method, we also report the synthesis of 2-pivaloylaminopterin-6- carbaldehyde.
On the development of NAD(P)H-sensitive fluorescent probes
Maidwell, Nicola L.,Reza Rezai,Roeschlaub, Carl A.,Sammes, Peter G.
, p. 1541 - 1546 (2007/10/03)
In contrast to current, multi-reagent assay systems, the development of a single reagent that can be used to assay NAD(P)H is described. The reagent eliminates the fluorophore 4-methylumbelliferone from a quinoxalinium adduct upon reduction and the chemistry of this process is described. The Royal Society of Chemistry.