Toluene-4-sulfonic acid 4-[2-(3-bromo-phenyl)-indolizine-3-carbonyl]-2-chloro-phenyl ester

Base Information

• Chemical Name: Toluene-4-sulfonic acid 4-[2-(3-bromo-phenyl)-indolizine-3-carbonyl]-2-chloro-phenyl ester
• CAS No.: 88273-88-5
• Molecular Formula: C₂₈H₁₉BrClNO₄S
• Molecular Weight: 580.886

Synonyms:Toluene-4-sulfonic acid 4-[2-(3-bromo-phenyl)-indolizine-3-carbonyl]-2-chloro-phenyl ester

Chemical Property of Toluene-4-sulfonic acid 4-[2-(3-bromo-phenyl)-indolizine-3-carbonyl]-2-chloro-phenyl ester

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Technology Process of Toluene-4-sulfonic acid 4-[2-(3-bromo-phenyl)-indolizine-3-carbonyl]-2-chloro-phenyl ester

There total 1 articles about Toluene-4-sulfonic acid 4-[2-(3-bromo-phenyl)-indolizine-3-carbonyl]-2-chloro-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Toluene-4-sulfonic acid 2-chloro-4-chlorocarbonyl-phenyl ester (77823-34-8) + 2-(3-bromophenyl)indolizine (80488-98-8) → Toluene-4-sulfonic acid 4-[2-(3-bromo-phenyl)-indolizine-3-carbonyl]-2-chloro-phenyl ester (88273-88-5)

Guidance literature:

In 1,2-dichloro-ethane; at 20 - 50 ℃; for 20h;

Reference yield:

Toluene-4-sulfonic acid 4-[2-(3-bromo-phenyl)-indolizine-3-carbonyl]-2-chloro-phenyl ester (88273-88-5) → Toluene-4-sulfonic acid 4-[1-bromo-2-(3-bromo-phenyl)-indolizine-3-carbonyl]-2-chloro-phenyl ester

Guidance literature:

With bromine; sodium acetate; In 1,4-dioxane; at 20 - 30 ℃; for 1.5h;

Reference yield:

Toluene-4-sulfonic acid 4-[2-(3-bromo-phenyl)-indolizine-3-carbonyl]-2-chloro-phenyl ester (88273-88-5) → Toluene-4-sulfonic acid 4-[2-(3-bromo-phenyl)-1-chloro-indolizine-3-carbonyl]-2-chloro-phenyl ester

Guidance literature:

With N-chloro-succinimide; In 1,2-dichloro-ethane; for 2h; Ambient temperature;

upstream raw materials:

Toluene-4-sulfonic acid 2-chloro-4-chlorocarbonyl-phenyl ester

2-(3-bromophenyl)indolizine

Downstream raw materials:

[2-(3-Bromo-phenyl)-indolizin-3-yl]-(3-chloro-4-hydroxy-phenyl)-methanone

[2-(3-Bromo-phenyl)-indolizin-3-yl]-[3-chloro-4-(3-dipropylamino-propoxy)-phenyl]-methanone; compound with oxalic acid

[2-(3-Bromo-phenyl)-indolizin-3-yl]-[3-chloro-4-(3-dibutylamino-propoxy)-phenyl]-methanone; compound with oxalic acid

[2-(3-Bromo-phenyl)-1-chloro-indolizin-3-yl]-(3-chloro-4-hydroxy-phenyl)-methanone

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