4'-Bromo-2-nitro-biphenyl

Base Information

• Chemical Name: 4'-Bromo-2-nitro-biphenyl
• CAS No.: 70873-41-5
• Molecular Formula: C₁₂H₈BrNO₂
• Molecular Weight: 278.105
• Mol file: 70873-41-5.mol

Synonyms:4-bromo-2-nitro-1-phenylbenzene

Chemical Property of 4'-Bromo-2-nitro-biphenyl

Chemical Property:

• Vapor Pressure: 4.21E-05mmHg at 25°C
• Melting Point: 59-60 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 123 °C(Press: 0.05 Torr)
• Density: 1.521±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

4′-Bromo-2-nitrobiphenyl AldrichCPR ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4'-Bromo-2-nitro-biphenyl

There total 9 articles about 4'-Bromo-2-nitro-biphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1,4-dibromo-2-nitrobenzene (3460-18-2) + phenylboronic acid (98-80-6) → 4-bromo-2-nitro-1-phenylbenzene (70873-41-5)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In ethanol; water; toluene; for 24h; Reflux;

Reference yield: 91.96%

4-bromo-1-iodo-2-nitrobenzene (112671-42-8) + phenylboronic acid (98-80-6) → 4-bromo-2-nitro-1-phenylbenzene (70873-41-5)

Guidance literature:

With potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; water; at 80 ℃; for 16h; Inert atmosphere;

Reference yield: 83.0%

ethyl-(4-bromo-2-nitro-phenyl)-sulfide + phenylboronic acid (98-80-6) → 4-bromo-2-nitro-1-phenylbenzene (70873-41-5)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; copper(I) thiophene-2-carboxylate; In methanol; at 22 ℃; for 2h; chemoselective reaction;

DOI:10.1039/c3sc50773d

upstream raw materials:

4-Bromo-2-nitroaniline

benzene

N-(4-bromo-2-nitrophenyl)acetamide

1,4-dibromo-2-nitrobenzene

Downstream raw materials:

4-bromo-2-amino-1,1'-biphenyl

9-ethyl-6-methyl-2-(2-phenylethynyl)-9H-carbazole-3-carbaldehyde

2-(4-chlorophenyl)-6-ethyl-9-methyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate

6-ethyl-9-methyl-3-phenyl-2-p-tolyl-6H-pyrido[4,3-b]carbazol-2-ium triflate