Oxazolo[5,4-d]pyrimidine, 5,7-dimethyl- (6CI)

Base Information

• Chemical Name: Oxazolo[5,4-d]pyrimidine, 5,7-dimethyl- (6CI)
• CAS No.: 120266-89-9
• Molecular Formula: C₇H₇N₃O
• Molecular Weight: 149.152
• Mol file: 120266-89-9.mol

Synonyms:Oxazolo[5,4-d]pyrimidine, 5,7-dimethyl- (6CI)

Chemical Property of Oxazolo[5,4-d]pyrimidine, 5,7-dimethyl- (6CI)

Chemical Property:

• PSA: 51.81000
• LogP: 1.23460

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Oxazolo[5,4-d]pyrimidine, 5,7-dimethyl- (6CI)

There total 3 articles about Oxazolo[5,4-d]pyrimidine, 5,7-dimethyl- (6CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(2,4-dimethyl-6-oxo-1,6-dihydro-pyrimidin-5-yl)-formamide (857435-50-8) → 5,7-dimethyl-oxazolo[5,4-d]pyrimidine (120266-89-9)

Guidance literature:

With trichlorophosphate;

DOI:10.1021/ja01139a049

Reference yield:

5-amino-2,6-dimethyl-3H-pyrimidin-4-one (93933-83-6) → 5,7-dimethyl-oxazolo[5,4-d]pyrimidine (120266-89-9)

Guidance literature:

Multi-step reaction with 2 steps

2: POCl₃

With trichlorophosphate;

DOI:10.1021/ja01139a049

Reference yield:

N-(2,4-dimethyl-6-oxo-1,6-dihydro-pyrimidin-5-yl)-formamide (857435-50-8) + trichlorophosphate (10025-87-3,12599-09-6,63736-95-8,39380-77-3) → 5,7-dimethyl-oxazolo[5,4-d]pyrimidine (120266-89-9)

Guidance literature:

DOI:10.1021/ja01139a049

upstream raw materials:

N-(2,4-dimethyl-6-oxo-1,6-dihydro-pyrimidin-5-yl)-formamide

trichlorophosphate

5-amino-2,6-dimethyl-3H-pyrimidin-4-one