dibenzylacetylene dicarboxylate

Base Information

• Chemical Name: dibenzylacetylene dicarboxylate
• CAS No.: 37976-44-6
• Molecular Formula: C₁₈H₁₄O₄
• Molecular Weight: 294.307
• Mol file: 37976-44-6.mol

Synonyms:dibenzylacetylene dicarboxylate

Chemical Property of dibenzylacetylene dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dibenzylacetylene dicarboxylate

There total 1 articles about dibenzylacetylene dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl alcohol (100-51-6,185532-71-2) + Acetylenedicarboxylic acid (142-45-0) → dibenzylacetylene dicarboxylate (37976-44-6)

Guidance literature:

With toluene-4-sulfonic acid; hydroquinone;

DOI:10.1039/P19730002024

Reference yield: 90.0%

trans-3-hexenoyl chloride (54716-04-0) + dibenzylacetylene dicarboxylate (37976-44-6) + methyllithium (917-54-4) → dibenzyl 2-(E)-hex-3-enoyl-3-methylmaleate

Guidance literature:

methyllithium; With copper(l) cyanide; In tetrahydrofuran; at -78 - -40 ℃; for 0.5h; Inert atmosphere;

dibenzylacetylene dicarboxylate; In tetrahydrofuran; at -78 ℃; Inert atmosphere;

trans-3-hexenoyl chloride; In tetrahydrofuran; at -78 - 0 ℃; Inert atmosphere;

DOI:10.1002/cmdc.202000801

Reference yield: 83.0%

dibenzylacetylene dicarboxylate (37976-44-6) + C15H17NO3 (1376458-74-0) → tetrabenzyl 4-ethyl-1-(4-methoxyphenyl)-7-methyl-1H-indole-2,3,5,6-tetracarboxylate

Guidance literature:

With copper(II) acetate monohydrate; In 5,5-dimethyl-1,3-cyclohexadiene; at 130 ℃; Schlenk technique;

DOI:10.1039/d0cc00512f

upstream raw materials:

benzyl alcohol

Acetylenedicarboxylic acid

Downstream raw materials:

(Z)-2-Methyl-3-((E)-pent-3-enoyl)-but-2-enedioic acid dibenzyl ester

(Z)-(R)-3-Benzyloxycarbonyl-2-methyl-4-triethylsilanyloxy-hex-2-enedioic acid 1-benzyl ester 6-((1R,2R)-1-isopropyl-2-methoxy-3-oxo-propyl) ester

C₅₅H₈₀O₁₃

C₅₅H₈₀O₁₄