1-(3,4-dichloro-phenyl)-cyclopentanecarbonyl chloride

Base Information

• Chemical Name: 1-(3,4-dichloro-phenyl)-cyclopentanecarbonyl chloride
• CAS No.: 437650-08-3
• Molecular Formula: C₁₂H₁₁Cl₃O
• Molecular Weight: 277.578
• Mol file: 437650-08-3.mol

Synonyms:1-(3,4-dichloro-phenyl)-cyclopentanecarbonyl chloride

Chemical Property of 1-(3,4-dichloro-phenyl)-cyclopentanecarbonyl chloride

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 1-(3,4-dichloro-phenyl)-cyclopentanecarbonyl chloride

There total 3 articles about 1-(3,4-dichloro-phenyl)-cyclopentanecarbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(3,4-dichlorophenyl)cyclopentanecarboxylic acid (437650-06-1) → 1-(3,4-dichloro-phenyl)-cyclopentanecarbonyl chloride (437650-08-3)

Guidance literature:

With thionyl chloride; In benzene; for 8h; Heating;

DOI:10.1023/A:1013728105186

Reference yield:

3,4-dichloro-benzeneacetonitrile (3218-49-3) → 1-(3,4-dichloro-phenyl)-cyclopentanecarbonyl chloride (437650-08-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 33 percent / NaOH / 12 h / 120 °C

2: 82 percent / KOH / ethane-1,2-diol / 10 h / Heating

3: SOCl₂ / benzene / 8 h / Heating

With potassium hydroxide; sodium hydroxide; thionyl chloride; In ethylene glycol; benzene;

DOI:10.1023/A:1013728105186

Reference yield:

1-(3,4-dichlorophenyl)cyclopentane-1-carbonitrile (213755-91-0) → 1-(3,4-dichloro-phenyl)-cyclopentanecarbonyl chloride (437650-08-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / KOH / ethane-1,2-diol / 10 h / Heating

2: SOCl₂ / benzene / 8 h / Heating

With potassium hydroxide; thionyl chloride; In ethylene glycol; benzene;

DOI:10.1023/A:1013728105186

upstream raw materials:

1-(3,4-dichlorophenyl)cyclopentanecarboxylic acid

3,4-dichloro-benzeneacetonitrile

1-(3,4-dichlorophenyl)cyclopentane-1-carbonitrile