Technology Process of 2-(2-(benzyloxy)ethyl)-1-tosylaziridine
There total 7 articles about 2-(2-(benzyloxy)ethyl)-1-tosylaziridine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
n-butyllithium; p-toluenesulfonyl chloride;
In
tetrahydrofuran; hexane;
for 1h;
Ambient temperature;
DOI:10.1021/ja9842464
- Guidance literature:
-
Multi-step reaction with 5 steps
1: MCPBA / CH2Cl2
2: 100 percent / aq. NaN3, NHCl / ethanol / 1 h / Heating
3: 1.) LiAlH4, 2.) H2O, NaF / 1.) ether, 0 deg C, 1 h, 2.) ether, 0 deg C, 30 min
4: 72 percent / pyridine / 7 h / Ambient temperature
5: 78 percent / BuLi, TsCl / tetrahydrofuran; hexane / 1 h / Ambient temperature
With
pyridine; lithium aluminium tetrahydride; n-butyllithium; sodium azide; water; sodium fluoride; p-toluenesulfonyl chloride; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; ethanol; hexane; dichloromethane;
DOI:10.1021/ja9842464
- Guidance literature:
-
Multi-step reaction with 6 steps
1: NaH / tetrahydrofuran
2: MCPBA / CH2Cl2
3: 100 percent / aq. NaN3, NHCl / ethanol / 1 h / Heating
4: 1.) LiAlH4, 2.) H2O, NaF / 1.) ether, 0 deg C, 1 h, 2.) ether, 0 deg C, 30 min
5: 72 percent / pyridine / 7 h / Ambient temperature
6: 78 percent / BuLi, TsCl / tetrahydrofuran; hexane / 1 h / Ambient temperature
With
pyridine; lithium aluminium tetrahydride; n-butyllithium; sodium azide; water; sodium hydride; sodium fluoride; p-toluenesulfonyl chloride; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; ethanol; hexane; dichloromethane;
DOI:10.1021/ja9842464
