(2-T-BUTYL-1-ETHYNYL)DIISOPROPOXYBORANE&

Base Information

• Chemical Name: (2-T-BUTYL-1-ETHYNYL)DIISOPROPOXYBORANE&
• CAS No.: 121021-24-7
• Molecular Formula: C12H23 B O2
• Molecular Weight: 210.124
• Hs Code.: 2931900090
• Mol file: 121021-24-7.mol

Synonyms:Boronicacid, (3,3-dimethyl-1-butynyl)-, bis(1-methylethyl) ester (9CI)

Chemical Property of (2-T-BUTYL-1-ETHYNYL)DIISOPROPOXYBORANE&

Chemical Property:

• Vapor Pressure: 0.102mmHg at 25°C
• Refractive Index: n20/D 1.4160(lit.)
• Boiling Point: 193-194 °C(lit.)
• Flash Point: 110 °F
• PSA: 18.46000
• Density: 0.891 g/mL at 25 °C(lit.)
• LogP: 2.91330
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

(3,3-Dimethyl-1-butynyl)boronic acid diisopropyl ester 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R10:
• Hazard Codes: R10:
• Statements: 10
• Safety Statements: 16-23-24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2-T-BUTYL-1-ETHYNYL)DIISOPROPOXYBORANE&

There total 1 articles about (2-T-BUTYL-1-ETHYNYL)DIISOPROPOXYBORANE& which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,3-Dimethylbut-1-yne (917-92-0) + Triisopropyl borate (5419-55-6) → diisopropyl (3,3-dimethylbut-1-yn-1-yl)boronate (121021-24-7)

Guidance literature:

3,3-Dimethylbut-1-yne; With n-butyllithium; In diethyl ether; hexane; at -78 ℃; for 3h; Inert atmosphere;

Triisopropyl borate; In diethyl ether; hexane; at -78 - 20 ℃; for 3h; Inert atmosphere;

DOI:10.1039/b803693d

Reference yield: 90.0%

sodium tetrafluoroborate (13755-29-8) + trifluoroborane diethyl ether (109-63-7) + diisopropyl (3,3-dimethylbut-1-yn-1-yl)boronate (121021-24-7) + triphenylbismuth(V) difluoride (2023-48-5,28719-53-1) → (C6H5)3BiC2C(CH3)3(1+)*BF4(1-)=[(C6H5)3BiC2C(CH3)3](BF4) (322399-12-2)

Guidance literature:

In dichloromethane; to a mixt. of Ph3BiF2 and BF3*OEt2 in CH2Cl2 ((CH3)2CHO)2BC2C(CH3)3 was added at 0°C, soln. stirred at room temp. for 15 h, aq. soln. of NaBF4 added, soln. vigorously stirred for 1 min; organic phase septd., dried ove MgSO4, concd. (reduced pressure), oily residue recrystd. from Et2O/CH2Cl2 (10/1); elem. anal.;

DOI:10.1039/b006881k

Reference yield: 49.0%

4-bromo-N-(2-sulfamoylphenyl)sulfonyl-benzamide (1154058-74-8) + diisopropyl (3,3-dimethylbut-1-yn-1-yl)boronate (121021-24-7) → 4-(3,3-Dimethylbut-1-ynyl)-N-(2-sulfamoylphenylsulfonyl)benzamide (1154059-17-2)

Guidance literature:

With sodium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In water; N,N-dimethyl-formamide; at 90 ℃; for 3h;

upstream raw materials:

3,3-Dimethylbut-1-yne

Triisopropyl borate

Downstream raw materials:

4,4-dimethylpent-2-yn-1-ol

(C₆H₅)3BiC₂C(CH₃)3⁽¹⁺⁾*BF₄^(1-)=[(C₆H₅)3BiC₂C(CH₃)3](BF₄)

dibenzyl 1-((1R,2S)-2-(3,3-dimethylbut-1-ynyl)cyclopent-3-enyl)hydrazine-1,2-dicarboxylate

4-(3,3-Dimethylbut-1-ynyl)-N-(2-sulfamoylphenylsulfonyl)benzamide

Refernces