2,6-Bis(methoxymethyl)-4-methyl-4-(2-oxoethoxy)-2,5-cyclohexadiene-1-one

Base Information

Chemical Name:2,6-Bis(methoxymethyl)-4-methyl-4-(2-oxoethoxy)-2,5-cyclohexadiene-1-one
CAS No.:881181-63-1
Molecular Formula:C₁₃H₁₈O₅
Molecular Weight:254.283
Hs Code.:
DSSTox Substance ID:DTXSID00469734
Nikkaji Number:J2.296.281G

Synonyms:881181-63-1;2,6-Bis(methoxymethyl)-4-methyl-4-(2-oxoethoxy)-2,5-cyclohexadiene-1-one;AGN-PC-00D0GE;DTXSID00469734

Suppliers and Price of 2,6-Bis(methoxymethyl)-4-methyl-4-(2-oxoethoxy)-2,5-cyclohexadiene-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,6-Bis(methoxymethyl)-4-methyl-4-(2-oxoethoxy)-2,5-cyclohexadiene-1-one

Chemical Property:

XLogP3:-0.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:254.11542367
Heavy Atom Count:18
Complexity:355

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(C=C(C(=O)C(=C1)COC)COC)OCC=O

Technology Process of 2,6-Bis(methoxymethyl)-4-methyl-4-(2-oxoethoxy)-2,5-cyclohexadiene-1-one

There total 5 articles about 2,6-Bis(methoxymethyl)-4-methyl-4-(2-oxoethoxy)-2,5-cyclohexadiene-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 941282-88-8
4-(2-hydroxy-ethoxy)-2,6-bis-methoxymethyl-4-methyl-cyclohexa-2,5-dienone

: 881181-63-1
(3,5-bismethoxymethyl-1-methyl-4-oxocyclohexa-2,5-dienyloxy)acetaldehyde

Guidance literature:: With Dess-Martin periodane; In dichloromethane; at 23 ℃; for 1h; Inert atmosphere;
DOI:10.1021/op600278f

Reference yield:

: 32449-09-5
2,6-bis(methoxymethyl)-4-methylphenol

: 881181-63-1
(3,5-bismethoxymethyl-1-methyl-4-oxocyclohexa-2,5-dienyloxy)acetaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: PhI(OAc)2 / CH₂Cl₂ / 2.5 h / 20 °C

2: 52 percent / Dess Martin periodinane / CH₂Cl₂ / 1 h / 20 °C

With [bis(acetoxy)iodo]benzene; Dess-Martin periodane; In dichloromethane; 2: Dess-Martin oxidation;
DOI:10.1021/ja058337u

Reference yield:

: 106-44-5
p-cresol

: 881181-63-1
(3,5-bismethoxymethyl-1-methyl-4-oxocyclohexa-2,5-dienyloxy)acetaldehyde

Guidance literature:: Multi-step reaction with 5 steps

1: 39 percent / aq. NaOH / 12 h

2: 94 percent / HCl / 12 h

3: 78 percent / NaOMe / 12 h

4: PhI(OAc)2 / CH₂Cl₂ / 2.5 h / 20 °C

5: 52 percent / Dess Martin periodinane / CH₂Cl₂ / 1 h / 20 °C

With hydrogenchloride; sodium hydroxide; [bis(acetoxy)iodo]benzene; sodium methylate; Dess-Martin periodane; In dichloromethane; 5: Dess-Martin oxidation;
DOI:10.1021/ja058337u