3-(tert-Butylamino-methyl)-5-(7-chloro-quinolin-4-ylamino)-4'-trifluoromethyl-biphenyl-2-ol; hydrochloride

Base Information

Chemical Name:3-(tert-Butylamino-methyl)-5-(7-chloro-quinolin-4-ylamino)-4'-trifluoromethyl-biphenyl-2-ol; hydrochloride
CAS No.:79287-57-3
Molecular Formula:C₂₇H₂₅ClF₃N₃O*2ClH
Molecular Weight:572.885
Hs Code.:

Synonyms:3-(tert-Butylamino-methyl)-5-(7-chloro-quinolin-4-ylamino)-4'-trifluoromethyl-biphenyl-2-ol; hydrochloride

Suppliers and Price of 3-(tert-Butylamino-methyl)-5-(7-chloro-quinolin-4-ylamino)-4'-trifluoromethyl-biphenyl-2-ol; hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(tert-Butylamino-methyl)-5-(7-chloro-quinolin-4-ylamino)-4'-trifluoromethyl-biphenyl-2-ol; hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(tert-Butylamino-methyl)-5-(7-chloro-quinolin-4-ylamino)-4'-trifluoromethyl-biphenyl-2-ol; hydrochloride

There total 6 articles about 3-(tert-Butylamino-methyl)-5-(7-chloro-quinolin-4-ylamino)-4'-trifluoromethyl-biphenyl-2-ol; hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 713-45-1
1-[(4-trifluoromethyl)phenyl]-2-propanone

: 79287-57-3
3-(tert-Butylamino-methyl)-5-(7-chloro-quinolin-4-ylamino)-4'-trifluoromethyl-biphenyl-2-ol; hydrochloride

Guidance literature:: Multi-step reaction with 6 steps

1: 67 percent / aq. sodium hydroxide / ethanol / 20 h

2: H₂ / Raney nickel / methanol

3: methanol

4: 81 percent / ethanol; H₂O / Heating

5: 6 N aq. HCl / Heating

6: ethanol / Heating

With hydrogenchloride; sodium hydroxide; hydrogen; nickel; In methanol; ethanol; water;
DOI:10.1021/jm00156a009

Reference yield:

: 79287-46-0
4-nitro-2-(4-trifluoromethylphenyl)phenol

: 79287-57-3
3-(tert-Butylamino-methyl)-5-(7-chloro-quinolin-4-ylamino)-4'-trifluoromethyl-biphenyl-2-ol; hydrochloride

Guidance literature:: Multi-step reaction with 5 steps

1: H₂ / Raney nickel / methanol

2: methanol

3: 81 percent / ethanol; H₂O / Heating

4: 6 N aq. HCl / Heating

5: ethanol / Heating

With hydrogenchloride; hydrogen; nickel; In methanol; ethanol; water;
DOI:10.1021/jm00156a009

Reference yield:

: 737748-72-0
5-Amino-4'-trifluoromethyl-biphenyl-2-ol

: 79287-57-3
3-(tert-Butylamino-methyl)-5-(7-chloro-quinolin-4-ylamino)-4'-trifluoromethyl-biphenyl-2-ol; hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: methanol

2: 81 percent / ethanol; H₂O / Heating

3: 6 N aq. HCl / Heating

4: ethanol / Heating

With hydrogenchloride; In methanol; ethanol; water;
DOI:10.1021/jm00156a009