Methanesulfonic acid (diethoxy-thiophosphoryl)-phenyl-methyl ester

Base Information

• Chemical Name: Methanesulfonic acid (diethoxy-thiophosphoryl)-phenyl-methyl ester
• CAS No.: 99668-38-9
• Molecular Formula: C₁₂H₁₉O₅PS₂
• Molecular Weight: 338.386
• Mol file: 99668-38-9.mol

Synonyms:Methanesulfonic acid (diethoxy-thiophosphoryl)-phenyl-methyl ester

Chemical Property of Methanesulfonic acid (diethoxy-thiophosphoryl)-phenyl-methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methanesulfonic acid (diethoxy-thiophosphoryl)-phenyl-methyl ester

There total 1 articles about Methanesulfonic acid (diethoxy-thiophosphoryl)-phenyl-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzaldehyde (100-52-7) → Methanesulfonic acid (diethoxy-thiophosphoryl)-phenyl-methyl ester (99668-38-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 97 percent / triethylamine / 2 h / 55 - 60 °C

2: triethylamine / CH₂Cl₂ / -40 - 0 °C

With triethylamine; In dichloromethane;

DOI:10.1021/jo00351a002

Reference yield: 95.0%

Methanesulfonic acid (diethoxy-thiophosphoryl)-phenyl-methyl ester (99668-38-9) → (Mercapto-phenyl-methyl)-phosphonic acid diethyl ester (70660-07-0)

Guidance literature:

With 2,6-dimethylpyridine; In water; acetone; at 60 ℃; for 16h;

DOI:10.1021/jo00351a002

Reference yield:

acetic acid (64-19-7,77671-22-8) + Methanesulfonic acid (diethoxy-thiophosphoryl)-phenyl-methyl ester (99668-38-9) → (Mercapto-phenyl-methyl)-phosphonic acid diethyl ester (70660-07-0) + Acetic acid (diethoxy-thiophosphoryl)-phenyl-methyl ester (99668-39-0)

Guidance literature:

With sodium acetate; acetic anhydride; at 50 ℃; for 24h;

DOI:10.1021/jo00351a002

upstream raw materials:

benzaldehyde

Downstream raw materials:

(Mercapto-phenyl-methyl)-phosphonic acid diethyl ester

Acetic acid (diethoxy-thiophosphoryl)-phenyl-methyl ester

Thioacetic acid S-[(diethoxy-phosphoryl)-phenyl-methyl] ester