C₁₉H₂₂O₇S

Base Information

• Chemical Name: C₁₉H₂₂O₇S
• CAS No.: 1354575-69-1
• Molecular Formula: C₁₉H₂₂O₇S
• Molecular Weight: 394.445
• Mol file: 1354575-69-1.mol

Synonyms:C₁₉H₂₂O₇S

Chemical Property of C₁₉H₂₂O₇S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₉H₂₂O₇S

There total 3 articles about C₁₉H₂₂O₇S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(R)-2,3-dihydroxy-2-methylpropyl 4-methoxybenzoate (1057675-74-7) + p-toluenesulfonyl chloride (98-59-9) → C19H22O7S (1354575-69-1)

Guidance literature:

With trimethylamine hydrochloride; triethylamine; In dichloromethane; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1038/ja.2011.90

Reference yield:

4-methoxybenzoic acid (100-09-4) → C19H22O7S (1354575-69-1)

Guidance literature:

Multi-step reaction with 3 steps

1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 2.5 h / 20 °C / Inert atmosphere

2: potassium osmate(VI) dihydrate; water; potassium carbonate; hydroquinidein 1,4-phthalazinediyl diether; potassium hexacyanoferrate(III) / tert-butyl alcohol / 4.5 h / 0 °C / Inert atmosphere

3: trimethylamine hydrochloride; triethylamine / dichloromethane / 3 h / 20 °C / Inert atmosphere

With dmap; potassium osmate(VI) dihydrate; water; trimethylamine hydrochloride; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; hydroquinidein 1,4-phthalazinediyl diether; triethylamine; potassium hexacyanoferrate(III); In dichloromethane; tert-butyl alcohol; 2: Sharpless dihydroxylation;

DOI:10.1038/ja.2011.90

Reference yield:

2-methyl-2-propenyl-4-methoxybenzoate (34301-32-1) → C19H22O7S (1354575-69-1)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium osmate(VI) dihydrate; water; potassium carbonate; hydroquinidein 1,4-phthalazinediyl diether; potassium hexacyanoferrate(III) / tert-butyl alcohol / 4.5 h / 0 °C / Inert atmosphere

2: trimethylamine hydrochloride; triethylamine / dichloromethane / 3 h / 20 °C / Inert atmosphere

With potassium osmate(VI) dihydrate; water; trimethylamine hydrochloride; potassium carbonate; hydroquinidein 1,4-phthalazinediyl diether; triethylamine; potassium hexacyanoferrate(III); In dichloromethane; tert-butyl alcohol; 1: Sharpless dihydroxylation;

DOI:10.1038/ja.2011.90

upstream raw materials:

(R)-2,3-dihydroxy-2-methylpropyl 4-methoxybenzoate

p-toluenesulfonyl chloride

2-methyl-2-propenyl-4-methoxybenzoate

4-methoxybenzoic acid