1-Chloro-3-(3-methoxyphenyl)propan-2-one

Base Information

Chemical Name:1-Chloro-3-(3-methoxyphenyl)propan-2-one
CAS No.:24253-16-5
Molecular Formula:C₁₀H₁₁ClO₂
Molecular Weight:198.649
Hs Code.:
European Community (EC) Number:966-255-3
DSSTox Substance ID:DTXSID401277355
Nikkaji Number:J3.375.683F

Synonyms:1-chloro-3-(3-methoxyphenyl)propan-2-one;24253-16-5;SCHEMBL3005839;POSNRFPMQFARTH-UHFFFAOYSA-N;DTXSID401277355;MFCD11935679;AKOS017515060;BS-52833;1-Chloro-3-(3-methoxyphenyl)-2-propanone;E73896;EN300-4258773;Z1255424725

Suppliers and Price of 1-Chloro-3-(3-methoxyphenyl)propan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 1-Chloro-3-(3-methoxyphenyl)propan-2-one

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:198.0447573
Heavy Atom Count:13
Complexity:170

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=CC(=C1)CC(=O)CCl

Technology Process of 1-Chloro-3-(3-methoxyphenyl)propan-2-one

There total 2 articles about 1-Chloro-3-(3-methoxyphenyl)propan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 67442-07-3
2-chloro-N-methoxy-N-methylacetamide

: 1798-09-0
m-methoxyphenylacetic acid

: 24253-16-5
1-chloro-3-(3-methoxyphenyl)propan-2-one

Guidance literature:: m-methoxyphenylacetic acid; With isopropylmagnesium chloride; In tetrahydrofuran; tert-butyl methyl ether; at -10 - 25 ℃; for 1.5h; Inert atmosphere; Schlenk technique;

2-chloro-N-methoxy-N-methylacetamide; In tetrahydrofuran; tert-butyl methyl ether; at 0 - 5 ℃; for 1.25h; Inert atmosphere; Schlenk technique;
DOI:10.1021/jo5016486

Reference yield: 71.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 6834-42-0
3-methoxyphenylacetic acid chloride

: 24253-16-5
1-chloro-3-(3-methoxyphenyl)propan-2-one

Guidance literature:: diazomethane; 3-methoxyphenylacetic acid chloride; In diethyl ether; at 20 ℃; for 2h;

With hydrogenchloride; In diethyl ether; at 5 ℃; for 0.25h;