(S)-2-<(2R,5S,6R)-6-<(S)-1-(4-methoxybenzyloxymethyl)ethyl>-5-methyltetrahydropyran-2-yl>butan-1-ol

Base Information

• Chemical Name: (S)-2-<(2R,5S,6R)-6-<(S)-1-(4-methoxybenzyloxymethyl)ethyl>-5-methyltetrahydropyran-2-yl>butan-1-ol
• CAS No.: 96181-81-6
• Molecular Formula: C₂₁H₃₄O₄
• Molecular Weight: 350.499

Synonyms:(S)-2-<(2R,5S,6R)-6-<(S)-1-(4-methoxybenzyloxymethyl)ethyl>-5-methyltetrahydropyran-2-yl>butan-1-ol

Chemical Property of (S)-2-<(2R,5S,6R)-6-<(S)-1-(4-methoxybenzyloxymethyl)ethyl>-5-methyltetrahydropyran-2-yl>butan-1-ol

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Technology Process of (S)-2-<(2R,5S,6R)-6-<(S)-1-(4-methoxybenzyloxymethyl)ethyl>-5-methyltetrahydropyran-2-yl>butan-1-ol

There total 19 articles about (S)-2-<(2R,5S,6R)-6-<(S)-1-(4-methoxybenzyloxymethyl)ethyl>-5-methyltetrahydropyran-2-yl>butan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

(S)-1-benzyloxy-2-<(2R,5S,6R)-6-<(S)-1-(4-methoxybenzyloxymethyl)-ethyl>-5-methyltetrahydropyran-2-yl>butane (96181-80-5) → (S)-2-<(2R,5S,6R)-6-<(S)-1-(4-methoxybenzyloxymethyl)ethyl>-5-methyltetrahydropyran-2-yl>butan-1-ol (96181-81-6)

Guidance literature:

With hydrogen; W-4 Raney Ni; In ethanol; for 2h; Ambient temperature;

DOI:10.1016/S0040-4039(01)91294-8

Reference yield: 96.0%

(2S,5S,6S)-2-benzyloxyethyl-5,6-dihydro-2-isopropyloxy-6-<2-(4-methoxybenzyloxy)-1(S)-methylethyl>-3-methyl-2H-pyran (96181-86-1) → (S)-2-<(2R,5S,6R)-6-<(S)-1-(4-methoxybenzyloxymethyl)ethyl>-5-methyltetrahydropyran-2-yl>butan-1-ol (96181-81-6)

Guidance literature:

With hydrogen; W-4 Raney Ni; In ethanol; for 2h; Ambient temperature;

DOI:10.1016/S0040-4020(01)90593-9

Reference yield: 96.0%

(2R,3R,6S)-6-((2R,5R,6S)-5-Benzyloxy-5-ethyl-6-methyl-tetrahydro-pyran-2-yl)-2-(4-methoxy-benzyloxy)-heptane-1,3,6-triol (120269-74-1) → (S)-2-<(2R,5S,6R)-6-<(S)-1-(4-methoxybenzyloxymethyl)ethyl>-5-methyltetrahydropyran-2-yl>butan-1-ol (96181-81-6)

Guidance literature:

With hydrogen; nickel; In ethanol; Ambient temperature;

DOI:10.1016/S0040-4039(00)80703-0

upstream raw materials:

(S)-1-benzyloxy-2-<(2R,5S,6R)-6-<(S)-1-(4-methoxybenzyloxymethyl)-ethyl>-5-methyltetrahydropyran-2-yl>butane

(2S,5S,6S)-2-benzyloxyethyl-5,6-dihydro-2-isopropyloxy-6-<2-(4-methoxybenzyloxy)-1(S)-methylethyl>-3-methyl-2H-pyran

(2R,3R,6S)-6-((2R,5R,6S)-5-Benzyloxy-5-ethyl-6-methyl-tetrahydro-pyran-2-yl)-2-(4-methoxy-benzyloxy)-heptane-1,3,6-triol

(2S,3S,4S)-5-Benzyloxy-2,4-dimethylpentan-1,3-diol

Downstream raw materials:

(R)-2-{(2R,5S,6R)-6-[(S)-2-(4-Methoxy-benzyloxy)-1-methyl-ethyl]-5-methyl-tetrahydro-pyran-2-yl}-butyric acid

salinomycin

C₅₈H₈₆O₁₃

C₅₇H₈₄O₁₂

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