96181-86-1

Upstream product

• 26530-60-9 trimethyl 2-phosphonopropionate 
• 108470-19-5 (2R,3R,4S)-2-C-(2-benzyloxyethyl)-3-formyloxy-5-(4-methoxybenzyloxy)-4-methylpentanal 
• 67-63-0 isopropyl alcohol 
• 113918-88-0 (R)-1-{(3aR,5S,6R,6aR)-6-[2-(benzyloxy)ethyl]-2,2-dimethyl-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl}ethane-1,2-diol 
• 113918-88-0 1-[(3aR,6R,6aR)-6-(2-Benzyloxy-ethyl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl]-ethane-1,2-diol 
• 113918-92-6 3-C-(2-benzyloxyethyl)-6-O-(tert-butyldimethylsilyl)-3,5-dideoxy-1,2-O-isopropylidene-5-C-toluenesulfonyloxymethyl-β-L-talofuranose 
• 113918-90-4 1-[(3aR,5S,6S,6aR)-6-(2-Benzyloxy-ethyl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl]-2-(tert-butyl-dimethyl-silanyloxy)-ethanone 
• 113918-94-8 3-C-(2-benzyloxyethyl)-3,5-dideoxy-1,2-O-isopropylidene-6-O-(4-methoxybenzyl)-5-C-methyl-β-D-talofuranose 
• 113918-97-1 (2Z,4S,5S,6S)-4-(2-benzyloxyethyl)-5-hydroxy-2,6-dimethyl-7-(4-methoxybenzyloxy)hept-2-enoic acid δ-lactone 
• 113918-93-7 3-C-(2-benzyloxyethyl)-5-C-(tert-butyldimethylsilyloxy)methyl-3,5-dideoxy-1,2-O-isopropylidene-α-D-allofuranose 
• 113918-89-1 (R)-1-{(3aR,5S,6R,6aR)-6-[2-(benzyloxy)ethyl]-2,2-dimethyl-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl}-2-tert-butyldimethylsilyloxyethanol 
• 113918-95-9 (2S,3R,4S,5R)-4-(2-Benzyloxy-ethyl)-5-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-tetrahydro-furan-2,3-diol 
• 113918-91-5 3-C-(2-benzyloxyethyl)-3,5-dideoxy-1,2-O-isopropylidene-5-methylene-α-D-ribo-hexofuranose 
• 108470-17-3 3-C-(2-benzyloxyethyl)-6-O-(tert-butyldimethylsilyl)-3,5-dideoxy-1,2-O-isopropylidene-5-methylene-α-D-ribo-hexofuranose 

Downstream Products

• 113918-99-3 5(S)-<2(tert-butyldimethylsilyloxy)ethyl>-5,6-dihydro-2(S)-isopropyloxy-6(R)-<2-(4-methoxybenzyloxy)-1(S)-methyl-1(S)-ethyl>-3-methyl-2H-pyran 
• 108470-24-2 5(S)-(5(R)-<2-(3,4-dimethoxybenzyloxy)ethyl>-2(S)-isopropyloxy-3(R)-methyl-6(S)-tetrahydropyranyl)-4(R)-hydroxy-1-hexene 
• 96182-02-4 (S)-2-[(2S,3R,5R,6S)-3-(2-Benzyloxy-ethyl)-6-isopropoxy-5-methyl-tetrahydro-pyran-2-yl]-propan-1-ol 
• 96181-78-1 5,6-dihydro-5(S)-(2-hydroxyethyl)-2(S)-isopropyloxy-6(R)-<2-(4-methoxybenzyloxy)-1(S)-methyl-1(S)-ethyl>-3-methyl-2H-pyran 
• 96182-01-3 (S)-2-[(2S,3S,6S)-3-(2-Benzyloxy-ethyl)-6-isopropoxy-5-methyl-3,6-dihydro-2H-pyran-2-yl]-propan-1-ol 
• 96181-99-6 (2S,3R,6S)-3-(2-Benzyloxy-ethyl)-6-isopropoxy-2-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-5-methyl-tetrahydro-pyran 
• 96182-00-2 (2S,3R,6S)-3-(2-Cyclohexylmethoxy-ethyl)-6-isopropoxy-2-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-5-methyl-tetrahydro-pyran 
• 123-11-5 4-methoxy-benzaldehyde 
• 96181-79-2 5(R)-(2-hydroxyethyl)-2(S)-isopropyloxy-6(S)-<2-(4-methoxybenzyloxy)-1(S)-methyl-1(S)-ethyl>-3-(R)-methyl-tetrahydropyran 
• 96243-61-7 5(R)-(2-hydroxyethyl)-2(S)-isopropyloxy-6(S)-<2-(4-methoxybenzyloxy)-1(S)-methyl-1(S)-ethyl>-3-(S)-methyl-tetrahydropyran 
• 96181-81-6 (S)-2-<(2R,5S,6R)-6-<(S)-1-(4-methoxybenzyloxymethyl)ethyl>-5-methyltetrahydropyran-2-yl>butan-1-ol 

Relevant academic research and scientific papers

TOTAL SYNTHESIS OF TYLONOLIDE, THE AGLYCONE OF THE 16-MEMBERED RING MACROLIDE TYLOSIN, FROM D-GLUCOSE. SELECTIVE APPLICATION OF MPM AND DMPM PROTECTING GROUPS FOR HYDROXY FUNCTIONS

Segments i (C11-C17) and ii (C1-C10), synthesized from D-glucose by employing some stereoselective reactions and benzyl-type protecting groups, were esterified and cyclized to the 16-membered enone , which was readily converted to tylonolide, the aglycone