BENZYLMETHYL-D3-AMINE HCL

Base Information

• Chemical Name: BENZYLMETHYL-D3-AMINE HCL
• CAS No.: 122025-10-9
• Molecular Formula: C₈H₁₁N*ClH
• Molecular Weight: 160.619
• Mol file: 122025-10-9.mol

Synonyms:BENZYLMETHYL-D3-AMINE HCL

Chemical Property of BENZYLMETHYL-D3-AMINE HCL

Chemical Property:

• PSA: 12.03000
• LogP: 2.59890

Purity/Quality:

Benzylmethyl-d3-amineHCl ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Benzylmethyl-d3-amine HCl (CAS# 122025-10-9) is a useful isotopically labeled research compound.

Technology Process of BENZYLMETHYL-D3-AMINE HCL

There total 3 articles about BENZYLMETHYL-D3-AMINE HCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

tert-butyl benzyl(methyl-d3)carbamate → C8H8(2)H3N*ClH (122025-10-9)

Guidance literature:

With hydrogenchloride; In water; ethyl acetate; at 0 - 20 ℃; Solvent;

Reference yield: 20.0%

methyl-d3 4-methylbenzenesulfonate (7575-93-1) + benzylamine (100-46-9) → C8H8(2)H3N*ClH (122025-10-9)

Guidance literature:

benzylamine; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h; Inert atmosphere;

methyl-d3 4-methylbenzenesulfonate; In N,N-dimethyl-formamide; at 0 - 20 ℃; Inert atmosphere;

Reference yield:

N-tert-butoxycarbonylbenzylamine (42116-44-9) → C8H8(2)H3N*ClH (122025-10-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium tert-butylate / N,N-dimethyl-formamide / 0.5 h / -20 °C / Inert atmosphere

1.2: -20 - 20 °C / Inert atmosphere

2.1: hydrogenchloride / ethyl acetate; water / 0 - 20 °C

With hydrogenchloride; potassium tert-butylate; In water; ethyl acetate; N,N-dimethyl-formamide;

upstream raw materials:

methyl-d3 4-methylbenzenesulfonate

benzylamine

N-tert-butoxycarbonylbenzylamine

Downstream raw materials:

methyl-d3-amine hydrochloride