Technology Process of C27H22F3NO4
There total 4 articles about C27H22F3NO4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C24H18F3NO2;
With
potassium tert-butylate;
In
tetrahydrofuran;
at 20 ℃;
for 1h;
Inert atmosphere;
chloroformic acid ethyl ester;
In
tetrahydrofuran;
for 0.5h;
Inert atmosphere;
DOI:10.1021/jm201179h
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: toluene-4-sulfonic acid / butan-1-ol / 24 h / 130 °C / Inert atmosphere
2.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate / 1,4-dioxane; water; toluene / 48 h / 90 °C / Inert atmosphere
3.1: potassium tert-butylate / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere
3.2: 0.5 h / Inert atmosphere
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium tert-butylate; potassium carbonate; toluene-4-sulfonic acid;
In
tetrahydrofuran; 1,4-dioxane; water; toluene; butan-1-ol;
DOI:10.1021/jm201179h
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate / 1,4-dioxane; water; toluene / 48 h / 90 °C / Inert atmosphere
2.1: potassium tert-butylate / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere
2.2: 0.5 h / Inert atmosphere
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium tert-butylate; potassium carbonate;
In
tetrahydrofuran; 1,4-dioxane; water; toluene;
DOI:10.1021/jm201179h
