5-Pyrimidinecarboximidamide,2-phenyl-,monohydrochloride(9CI)

Base Information

• Chemical Name: 5-Pyrimidinecarboximidamide,2-phenyl-,monohydrochloride(9CI)
• CAS No.: 122773-94-8
• Molecular Formula: C11H10 N4 . Cl H
• Molecular Weight: 0
• Mol file: 122773-94-8.mol

Synonyms:5-Pyrimidinecarboximidamide,2-phenyl-, monohydrochloride (9CI)

Chemical Property of 5-Pyrimidinecarboximidamide,2-phenyl-,monohydrochloride(9CI)

Chemical Property:

• PSA: 75.65000
• LogP: 3.02970

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Pyrimidinecarboximidamide,2-phenyl-,monohydrochloride(9CI)

There total 1 articles about 5-Pyrimidinecarboximidamide,2-phenyl-,monohydrochloride(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Phenyl-pyrimidine-5-carboximidic acid ethyl ester; hydrochloride → 5-amidino-2-phenylpyrimidine hydrochloride (122773-94-8)

Guidance literature:

With sodium hydroxide; ammonium chloride; Yield given. Multistep reaction; 1) chloroform, water, 30 min. 2) water, ethanol, reflux 1 h;

DOI:10.1007/BF00475329

Reference yield: 80.0%

5-amidino-2-phenylpyrimidine hydrochloride (122773-94-8) + 1,3-bis(dimethylamino)-2-phenylpropene perchlorate (122774-07-6) → 2',5-diphenyl-2,5'-bipyrimidine (122774-09-8)

Guidance literature:

With sodium methylate; In methanol; for 1h; Heating;

DOI:10.1007/BF00475329

Reference yield: 41.0%

ethanol (64-17-5) + 5-amidino-2-phenylpyrimidine hydrochloride (122773-94-8) → 2-phenylpyrimidine-5-carboxylic acid ethyl ester (85386-14-7) + 2-phenylpyrimidine-5-carboxylic acid amide (122773-96-0)

Guidance literature:

With piperidine; nitromalondialdehyde sodium salt; In 1,4-dioxane; at 20 ℃; for 3h;

DOI:10.1007/BF00529883

Downstream raw materials:

2-phenylpyrimidine-5-carboxylic acid ethyl ester

2-phenylpyrimidine-5-carboxylic acid amide

2',5-diphenyl-2,5'-bipyrimidine

5-nitro-2'-phenyl-2,5'-bipyrimidine