2-(4-chloro-6-{{[(1,1-dimethylethyl)oxy]carbonyl}[2-fluoro-4-(methylsulfonyl)phenyl]amino}-5-pyrimidinyl)ethyl methanesulfonate

Base Information

Chemical Name:2-(4-chloro-6-{{[(1,1-dimethylethyl)oxy]carbonyl}[2-fluoro-4-(methylsulfonyl)phenyl]amino}-5-pyrimidinyl)ethyl methanesulfonate
CAS No.:1001397-18-7
Molecular Formula:C₁₉H₂₃ClFN₃O₇S₂
Molecular Weight:523.991
Hs Code.:

Synonyms:2-(4-chloro-6-{{[(1,1-dimethylethyl)oxy]carbonyl}[2-fluoro-4-(methylsulfonyl)phenyl]amino}-5-pyrimidinyl)ethyl methanesulfonate

Suppliers and Price of 2-(4-chloro-6-{{[(1,1-dimethylethyl)oxy]carbonyl}[2-fluoro-4-(methylsulfonyl)phenyl]amino}-5-pyrimidinyl)ethyl methanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(4-chloro-6-{{[(1,1-dimethylethyl)oxy]carbonyl}[2-fluoro-4-(methylsulfonyl)phenyl]amino}-5-pyrimidinyl)ethyl methanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(4-chloro-6-{{[(1,1-dimethylethyl)oxy]carbonyl}[2-fluoro-4-(methylsulfonyl)phenyl]amino}-5-pyrimidinyl)ethyl methanesulfonate

There total 1 articles about 2-(4-chloro-6-{{[(1,1-dimethylethyl)oxy]carbonyl}[2-fluoro-4-(methylsulfonyl)phenyl]amino}-5-pyrimidinyl)ethyl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1001397-16-5
1,1-dimethylethyl [6-chloro-5-(2-hydroxyethyl)-4-pyrimidinyl][2-fluoro-4-(methylsulfonyl)phenyl]carbamate

: 7143-01-3
Methanesulfonic anhydride

: 1001397-18-7
2-(4-chloro-6-{{[(1,1-dimethylethyl)oxy]carbonyl}[2-fluoro-4-(methylsulfonyl)phenyl]amino}-5-pyrimidinyl)ethyl methanesulfonate

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 5 - 20 ℃; for 15h;

Reference yield: 89.0%

: 1001397-18-7
2-(4-chloro-6-{{[(1,1-dimethylethyl)oxy]carbonyl}[2-fluoro-4-(methylsulfonyl)phenyl]amino}-5-pyrimidinyl)ethyl methanesulfonate

: 1001397-19-8
4-chloro-7-[2-fluoro-4-(methylsulfonyl)phenyl]-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine

Guidance literature:: 2-(4-chloro-6-{{[(1,1-dimethylethyl)oxy]carbonyl}[2-fluoro-4-(methylsulfonyl)phenyl]amino}-5-pyrimidinyl)ethyl methanesulfonate; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 3h;

With triethylamine; In dichloromethane; at 20 ℃; for 2h;