7143-01-3

Basic information

• Product Name: Methanesulfonic anhydride
• Synonyms: METHANESULPHONIC ANHYDRIDE;METHANESULFONIC ANHYDRIDE;METHYLSULFONIC ANHYDRIDE;Mesyl anhydride;Methanesulfonic acid, anhydride;methanesulfonicacid,anhydride;Mesic anhydride;Methanesulfonic anhydride, 98+%
• CAS NO: 7143-01-3
• Molecular Formula: C₂H₆O₅S₂
• Molecular Weight: 174.2
• EINECS: 230-442-1
• Product Categories: Organic Building Blocks;Sulfonic/Sulfinic Acid Anhydrides;Sulfur Compounds
• Mol File: 7143-01-3.mol
• Article Data: 13

Chemical Properties

• Melting Point: 64-67 °C(lit.)
• Boiling Point: 125 °C4 mm Hg(lit.)
• Flash Point: 125°C/4mm
• Appearance: White to light brown to gray/Powder, Crystals and/or Chunks
• Density: 1,36 g/cm3
• Vapor Density: 3.3 (vs air)
• Vapor Pressure: 0.00386mmHg at 25°C
• Refractive Index: 1.5300 (estimate)
• Storage Temp.: Store at
• Solubility: Soluble in organic solvents.
• Sensitive: Moisture Sensitive
• BRN: 972316
• CAS DataBase Reference: Methanesulfonic anhydride(CAS DataBase Reference)
• NIST Chemistry Reference: Methanesulfonic anhydride(7143-01-3)
• EPA Substance Registry System: Methanesulfonic anhydride(7143-01-3)

Safety Data

• Hazard Codes: C
• Statements: 14-35
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• F: 3-10
• TSCA: Yes
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 7143-01-3(Hazardous Substances Data)

Usage

Chemical Properties

white to light brown to grey powder, crystals and/

Uses

Methanesulfonic anhydride is used to prepare methylsulfonyl esters called as mesylates. It finds application in the reaction of aromatic alkylation. It reacts with dimethylsulfoxide to get sulfoxonium complex, which is a useful oxidizing agent.

InChI:InChI=1/C2H6O5S2/c1-8(3,4)7-9(2,5)6/h1-2H3

Upstream product

• 3315-16-0 silver cyanate 
• 124-63-0 methanesulfonyl chloride 
• 75-76-3 tetramethylsilane 
• 2206-26-0 [D₃]acetonitrile 
• 1001-62-3 bis(methanesulfonyl)peroxide 
• 624-92-0 Dimethyldisulphide 
• 10028-15-6 ozone 
• 7446-11-9 sulfur trioxide 
• 865-52-1 tetramethylgermane 
• 34557-54-5 methane 
• 96042-30-7 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran 
• 71-43-2 benzene 
• 75-75-2 methanesulfonic acid 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 62-50-0 Ethyl methanesulfonate 
• 124-63-0 methanesulfonyl chloride 
• 57337-91-4 diethyl 2-<(methylsulfonyl)oxy>-2-(p-nitrophenyl)ethylene-1,1-dicarboxylate 
• 55-98-1 busulfan 
• 13098-28-7 3,3'-Dimesyloxy-N-methyl-dipropylamin 
• 918-05-8 N,N-dimethylmethanesulfonamide 
• 32300-42-8 1-Phenylthio-2-mesyloxypropan 
• 32300-44-0 1-p-Anisylthio-2-mesyloxypropan 
• 32300-45-1 1-p-Methylthiophenylthio-2-mesyloxypropan 
• 32300-43-9 1-p-Chlorphenylthio-2-mesyloxypropan 
• 5554-83-6 (methylsulfonylmethylene)triphenylphosphorane 
• 51848-88-5 α-(p-Methoxybenzylsulfonyl)-methylidentriphenylphosphoran 
• 51848-96-5 α-Neopentylsulfonyl-methylidentriphenylphosphoran 
• 51848-95-4 α-1-Adamantylmethylsulfonyl-methylidentriphenylphosphoran 

Relevant articles and documents

PROCESS FOR PROVIDING ANHYDROUS ALKANE SULFONIC ACIDS IN PURIFIED FORM

The present application refers to a process for providing anhydrous alkane sulfonic acid in purified form.

COMPOSITIONS AND METHODS FOR SILENCING APOLIPOPROTEIN B

The present invention provides compositions and methods for the delivery of interfering RNAs that silence APOB expression to liver cells. In particular, the nucleic acid-lipid particles provide efficient encapsulation of nucleic acids and efficient delivery of the encapsulated nucleic acid to cells in vivo. The compositions of the present invention are highly potent, thereby allowing effective knock-down of APOB at relatively low doses. In addition, the compositions and methods of the present invention are less toxic and provide a greater therapeutic index compared to compositions and methods previously known in the art.

Active ray curable ink-jet composition, image forming method using the same, ink-jet recording apparatus, and triarylsulfonium salt compound

An active ray curable ink-jet ink composition comprising a photo-induced acid generating agent containing an onium salt which does not generate benzene under active ray radiation, and a photopolymerizable compound containing a compound having an oxetane ring in the molecule.