Technology Process of benzyl 3,23-dihydroxy-lup-20(29)-en-28-oate
There total 6 articles about benzyl 3,23-dihydroxy-lup-20(29)-en-28-oate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 24h;
Inert atmosphere;
- Guidance literature:
-
With
dihydrogen peroxide; potassium hydrogencarbonate;
In
methanol;
at 50 ℃;
for 12h;
Inert atmosphere;
DOI:10.1002/anie.201407016
- Guidance literature:
-
Multi-step reaction with 4 steps
1: potassium carbonate / N,N-dimethyl-formamide / 3.5 h / 60 °C / Inert atmosphere
2: (1,5-cyclooctadiene)(methoxy)iridium(I) dimer / toluene / 12 h / 20 °C / Inert atmosphere; Sealed tube
3: (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 3,4,7,8-Tetramethyl-o-phenanthrolin; norborn-2-ene / tetrahydrofuran / 37 h / 20 - 120 °C / Sealed tube; Inert atmosphere
4: potassium hydrogencarbonate; dihydrogen peroxide / methanol / 12 h / 50 °C / Inert atmosphere
With
norborn-2-ene; (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 3,4,7,8-Tetramethyl-o-phenanthrolin; dihydrogen peroxide; potassium carbonate; potassium hydrogencarbonate;
In
tetrahydrofuran; methanol; N,N-dimethyl-formamide; toluene;
4: |Fleming-Tamao Oxidation;
DOI:10.1002/anie.201407016
