N₄-benzoyl-5'-O-(DMT)-2'-N,4'-C-[(N-methoxyamino)methylene]cytidine-3'-[(2-cyanoethyl)-N,N-diisopropyl]phosphoramidite

Base Information

• Chemical Name: N₄-benzoyl-5'-O-(DMT)-2'-N,4'-C-[(N-methoxyamino)methylene]cytidine-3'-[(2-cyanoethyl)-N,N-diisopropyl]phosphoramidite
• CAS No.: 1091608-05-7
• Molecular Formula: C₄₈H₅₅N₆O₉P
• Molecular Weight: 890.973

Synonyms:N₄-benzoyl-5'-O-(DMT)-2'-N,4'-C-[(N-methoxyamino)methylene]cytidine-3'-[(2-cyanoethyl)-N,N-diisopropyl]phosphoramidite

Chemical Property of N₄-benzoyl-5'-O-(DMT)-2'-N,4'-C-[(N-methoxyamino)methylene]cytidine-3'-[(2-cyanoethyl)-N,N-diisopropyl]phosphoramidite

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Technology Process of N₄-benzoyl-5'-O-(DMT)-2'-N,4'-C-[(N-methoxyamino)methylene]cytidine-3'-[(2-cyanoethyl)-N,N-diisopropyl]phosphoramidite

There total 1 articles about N₄-benzoyl-5'-O-(DMT)-2'-N,4'-C-[(N-methoxyamino)methylene]cytidine-3'-[(2-cyanoethyl)-N,N-diisopropyl]phosphoramidite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

N4-benzoyl-5'-O-(DMT)-2'-N,4'-C-[(N-methoxyamino)methylene]cytidine (1091608-04-6) + N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite (102691-36-1) → N4-benzoyl-5'-O-(DMT)-2'-N,4'-C-[(N-methoxyamino)methylene]cytidine-3'-[(2-cyanoethyl)-N,N-diisopropyl]phosphoramidite (1091608-05-7)

Guidance literature:

With 1-methyl-1H-imidazole; 1H-tetrazole; In N,N-dimethyl-formamide; at 20 ℃; for 6h;

upstream raw materials:

N₄-benzoyl-5'-O-(DMT)-2'-N,4'-C-[(N-methoxyamino)methylene]cytidine

N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite

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