Technology Process of (1R,2R,3S)-3-amino-1-(tert-butyldimethylsilyloxy)-1-methylcyclohexan-2-ol
There total 7 articles about (1R,2R,3S)-3-amino-1-(tert-butyldimethylsilyloxy)-1-methylcyclohexan-2-ol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
palladium on carbon; hydrogen;
In
ethyl acetate;
under 760.051 Torr;
- Guidance literature:
-
In
ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1H-2,2,4-triazole; dmap / N,N-dimethyl-formamide / 20 °C
2: 3-chloro-benzenecarboperoxoic acid; sodium hydrogencarbonate / dichloromethane / 20 h / 20 °C / Inert atmosphere
3: sodium azide; ammonium chloride / water; methanol / 12 h / 60 °C
4: hydrogen; palladium on carbon / ethyl acetate / 760.05 Torr
With
dmap; sodium azide; palladium on carbon; hydrogen; sodium hydrogencarbonate; ammonium chloride; 1H-2,2,4-triazole; 3-chloro-benzenecarboperoxoic acid;
In
methanol; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide;