2,2'-(2,3-Naphthylenedioxy)diphenol bis(methyl ether)

Base Information

• Chemical Name: 2,2'-(2,3-Naphthylenedioxy)diphenol bis(methyl ether)
• CAS No.: 131354-68-2
• Molecular Formula: C₂₄H₂₀O₄
• Molecular Weight: 372.42
• Mol file: 131354-68-2.mol

Synonyms:2,2'-(2,3-Naphthylenedioxy)diphenol bis(methyl ether)

Chemical Property of 2,2'-(2,3-Naphthylenedioxy)diphenol bis(methyl ether)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2'-(2,3-Naphthylenedioxy)diphenol bis(methyl ether)

There total 1 articles about 2,2'-(2,3-Naphthylenedioxy)diphenol bis(methyl ether) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.8%

2,3-dibromonaphthalene (13214-70-5) + 2-methoxy-phenol (90-05-1) → 2,2'-(2,3-Naphthylenedioxy)diphenol bis(methyl ether) (131354-68-2)

Guidance literature:

With 1,3-dimethyl-2-imidazolinone; at 170 - 180 ℃; for 46h;

DOI:10.1021/jo00003a055

Reference yield: 97.0%

2,2'-(2,3-Naphthylenedioxy)diphenol bis(methyl ether) (131354-68-2) → C22H16O4 (131354-69-3)

Guidance literature:

With boron tribromide; In dichloromethane; at 0 ℃; for 3h;

DOI:10.1021/jo00003a055

Reference yield:

2,2'-(2,3-Naphthylenedioxy)diphenol bis(methyl ether) (131354-68-2) → 2-(2-{3-[2-(2-Hydroxy-ethoxy)-phenoxy]-naphthalen-2-yloxy}-phenoxy)-ethanol (131354-83-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 97 percent / BBr₃ / CH₂Cl₂ / 3 h / 0 °C

2: 1.) Cs₂CO₃ / 1.) DMF, 80 deg C, 1 h, 2.) 80 deg C, 6 h

3: 82 percent / hydrogen / 10 percent Pd/C / ethyl acetate / 4 h / 25 °C / 2280 Torr

With hydrogen; boron tribromide; caesium carbonate; palladium on activated charcoal; In dichloromethane; ethyl acetate;

DOI:10.1021/jo00003a055

upstream raw materials:

2,3-dibromonaphthalene

2-methoxy-phenol

Downstream raw materials:

C₂₂H₁₆O₄

2-(2-{3-[2-(2-Hydroxy-ethoxy)-phenoxy]-naphthalen-2-yloxy}-phenoxy)-ethanol

2,3-Bis-[2-(2-benzyloxy-ethoxy)-phenoxy]-naphthalene

C₃₃H₂₉NO₆*C₇H₅N

Refernces