Technology Process of Pyrido[1,2-a]benzimidazol-8-ol (9CI)
There total 6 articles about Pyrido[1,2-a]benzimidazol-8-ol (9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
boron tribromide;
In
dichloromethane;
at -20 - 25 ℃;
for 6h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; potassium tert-butylate / toluene / 14 h / 110 °C / Inert atmosphere
2: 1,1,1,3',3',3'-hexafluoro-propanol; iodobenzene; 3-chloro-benzenecarboperoxoic acid / 2 h / 25 °C
3: boron tribromide / dichloromethane / 6 h / -20 - 25 °C
With
iodobenzene; 1,1,1,3',3',3'-hexafluoro-propanol; potassium tert-butylate; palladium diacetate; boron tribromide; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; 3-chloro-benzenecarboperoxoic acid;
In
dichloromethane; toluene;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1,1,1,3',3',3'-hexafluoro-propanol; iodobenzene; 3-chloro-benzenecarboperoxoic acid / 2 h / 25 °C
2: boron tribromide / dichloromethane / 6 h / -20 - 25 °C
With
iodobenzene; 1,1,1,3',3',3'-hexafluoro-propanol; boron tribromide; 3-chloro-benzenecarboperoxoic acid;
In
dichloromethane;
