1-AMINO-2,2-DIMETHYLCYCLOPROPANECARBOXYLIC ACID

Base Information

• Chemical Name: 1-AMINO-2,2-DIMETHYLCYCLOPROPANECARBOXYLIC ACID
• CAS No.: 123445-53-4
• Molecular Formula: C6H11 N O2
• Molecular Weight: 129.159
• Hs Code.: 2922499990
• Mol file: 123445-53-4.mol

Synonyms:1-AMINO-2,2-DIMETHYLCYCLOPROPANECARBOXYLIC ACID;Cyclopropanecarboxylic acid, 1-amino-2,2-dimethyl- (9CI)

Chemical Property of 1-AMINO-2,2-DIMETHYLCYCLOPROPANECARBOXYLIC ACID

Chemical Property:

• PSA: 63.32000
• LogP: 0.89870

Purity/Quality:

95% ^*data from raw suppliers

1-Amino-2,2-dimethylcyclopropanecarboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-AMINO-2,2-DIMETHYLCYCLOPROPANECARBOXYLIC ACID

There total 30 articles about 1-AMINO-2,2-DIMETHYLCYCLOPROPANECARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

1-(N-tert-butylamino)-2,2-dimethylcyclopropane-1-carbonitrile (123445-50-1) → (+/-)-2,2-dimethyl-1-aminocyclopropane-1-carboxylic acid (123445-53-4)

Guidance literature:

With hydrogenchloride; for 120h; Heating;

DOI:10.1016/S0040-4039(00)99600-X

Reference yield: 60.0%

1-amino-2,2-dimethylcyclopropanecarbonitrile (131149-82-1) → (+/-)-2,2-dimethyl-1-aminocyclopropane-1-carboxylic acid (123445-53-4)

Guidance literature:

With hydrogenchloride; for 72h; Heating;

DOI:10.1016/S0040-4020(01)86477-2

Reference yield: 20.0%

1-(N-tert-butylamino)-2,2-dimethylcyclopropane-1-carbonitrile (123445-50-1) → 2-amino-4-hydroxy-4-methylpentanoic acid (104302-37-6) + (+/-)-2,2-dimethyl-1-aminocyclopropane-1-carboxylic acid (123445-53-4)

Guidance literature:

With hydrogenchloride; for 72h; Yields of byproduct given; Heating;

DOI:10.1021/jo00309a023

upstream raw materials:

1-(N-tert-butylamino)-2,2-dimethylcyclopropane-1-carbonitrile

2,2-Dimethyl-1-(2,2,2-trifluoro-acetylamino)-cyclopropanecarboxylic acid

N-(2,2-dimethyl-1-phenyl-1-cyclopropyl)trifluoroacetamide

N-<2,2-dimethyl-1-(4-methylphenyl)-1-cyclopropyl>trifluoroacetamide

Downstream raw materials:

C₉H₁₉NO₂Si

4-methyl-2-oxopentanoic acid

(+)-(R)-2,2-Dimethyl-1-aminocyclopropane-1-carboxylic acid

3-amino-5,5-dimethyltetrahydro-2-furanone

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