104302-37-6Relevant articles and documents
Synthesis of 2,2-Dialkyl-1-aminocyclopropanecarboxylic Acids from α-Chloro Ketimines
Kimpe, Norbert De,Sulmon, Paul,Brunet, Pascal
, p. 5777 - 5784 (1990)
2,2-Dialkyl-1-aminocyclopropanecarboxylic acids, abbreviated as 2,2-dialkyl Acc's, are potential plant growth regulators which were synthesized by ring closure of α-chloro imines.The synthetic scheme leading to these Acc analogues entails a newly developed regiospecific synthesis of tertiary α-chloro ketimines, the trapping with cyanide of a transient Favorskii derived cyclopropylideneamine, and the hydrolytic conversion of 1-(N-tert-butylamino)-2,2-dialkylcyclopropanecarbonitriles into the title compounds.
