4-AMINO-2,5-DIMETHOXYANILINE

Base Information

• Chemical Name: 4-AMINO-2,5-DIMETHOXYANILINE
• CAS No.: 17626-02-7
• Molecular Formula: C8H12 N2 O2
• Molecular Weight: 168.195
• Hs Code.: 2922299090
• Mol file: 17626-02-7.mol

Synonyms:p-Phenylenediamine,2,5-dimethoxy- (8CI); 2,5-Dimethoxy-1,4-diaminobenzene;2,5-Dimethoxy-1,4-phenylenediamine; 2,5-Dimethoxy-p-phenylenediamine

Chemical Property of 4-AMINO-2,5-DIMETHOXYANILINE

Chemical Property:

• Vapor Pressure: 0.000102mmHg at 25°C
• Melting Point: 212.5-214 °C
• Boiling Point: 337.9°C at 760 mmHg
• PKA: 5.68±0.10(Predicted)
• Flash Point: 182.2°C
• PSA: 70.50000
• Density: 1.184g/cm³
• LogP: 2.03060

Purity/Quality:

99% ^*data from raw suppliers

2,5-Dimethoxybenzene-1,4-diamine 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-AMINO-2,5-DIMETHOXYANILINE

There total 10 articles about 4-AMINO-2,5-DIMETHOXYANILINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2,5-dinitro-1,4-dimethoxybenzene (56741-26-5) → 2,5-dimethoxy-p-phenylenediamine (17626-02-7)

Guidance literature:

With hydrogen; palladium(II) hydroxide; In methanol; ethyl acetate; at 25 ℃; for 6h; under 45.0045 Torr;

DOI:10.1016/j.tet.2013.04.025

Reference yield: 88.0%

2,5-dimethoxy-4-nitroaniline (6313-37-7) → 2,5-dimethoxy-p-phenylenediamine (17626-02-7)

Guidance literature:

With hydrogen; platinum on activated charcoal; In ethanol; for 15h; under 1520.1 Torr;

DOI:10.1021/ja001298w

Reference yield:

C10H11F3N2O3 (1263321-07-8) → 2,5-dimethoxy-p-phenylenediamine (17626-02-7)

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; methanol; at 20 ℃; for 1h;

DOI:10.1016/j.tet.2010.11.046

upstream raw materials:

1,4-dimethoxybezene

2,5-dimethoxy-4-nitroaniline

2,5-dinitro-1,4-dimethoxybenzene

C₁₀H₉F₃N₂O₅

Downstream raw materials:

N,N'-(2,5-dimethoxy-p-phenylene)-bis-acetoacetamide

2,5-bishydroquinone dimethylether

N,N'-(2,5-dimethoxy-1,4-phenylene)bis(3-oxo-3H-naphtho[2,1-b]pyran-2-carboxamide)

C₆₆H₁₀₄N₂O₆

Refernces

• 1、 Kolmer-Anderl, Nicole,Kolmer, Andreas,Thiele, Christina M.,Rehahn, Matthias. "Exploration of the Photodegradation of Naphtho[2,3-g] quinoxalines and Pyrazino[2,3-b]phenazines". supporting information. p. 5277 - 5287. Retrieved 2016/04/09.
• 2、 Wang, Gui-Tao,Zhao, Xin,Li, Zhan-Ting. "Hydrogen bonded arylamide-linked cholesteryl dimesogenic liquid crystals: A study of the length and side chain effects". . p. 48 - 57. Retrieved 2011/03/17.