(+/-)-CIS-3-METHYL-2-PIPERIDINECARBOXYLIC ACID

Base Information

Chemical Name:(+/-)-CIS-3-METHYL-2-PIPERIDINECARBOXYLIC ACID
CAS No.:123719-65-3
Molecular Formula:C₇H₁₃NO₂
Molecular Weight:143.186
Hs Code.:
Mol file:123719-65-3.mol

Synonyms:2-Piperidinecarboxylicacid, 3-methyl-, cis- (9CI); 2-Piperidinecarboxylic acid, 3-methyl-, cis-(?à)-

Suppliers and Price of (+/-)-CIS-3-METHYL-2-PIPERIDINECARBOXYLIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(2R,3S)-3-Methylpiperidine-2-carboxylicacid 95+%
1g
$ 475.00

American Custom Chemicals Corporation
(+/-)-CIS-3-METHYL-2-PIPERIDINECARBOXYLIC ACID 95.00%
2G
$ 1559.25

Total 3 raw suppliers

Chemical Property of (+/-)-CIS-3-METHYL-2-PIPERIDINECARBOXYLIC ACID

Chemical Property:

PSA：49.33000
LogP:0.78790

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

(2R,3S)-3-Methylpiperidine-2-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (+/-)-CIS-3-METHYL-2-PIPERIDINECARBOXYLIC ACID

There total 4 articles about (+/-)-CIS-3-METHYL-2-PIPERIDINECARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 123811-72-3
3-methylpicolinic acid hydrochloride

: 123719-65-3,147428-62-4
cis-3-methyl-2-piperidinecarboxylic acid

Guidance literature:: With hydrogen; platinum(IV) oxide; In ethanol; water; at 60 ℃; for 24h; under 3102.9 Torr;
DOI:10.1021/jo00289a058

Reference yield: 34.0%

: 4021-07-2
3-methyl-pyridine-2-carboxylic acid

: 123719-65-3,147428-62-4
cis-3-methyl-2-piperidinecarboxylic acid

Guidance literature:: With platinum(IV) oxide; hydrogen; In ethanol; at 60 ℃; for 24h; under 3102.97 Torr;
DOI:10.1016/j.bmc.2011.10.022

Reference yield:

: 1003-73-2
3-picoline-N-oxide

: 123719-65-3,147428-62-4
cis-3-methyl-2-piperidinecarboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: dimethylcarbamyl chloride / CH₂Cl₂ / 24 h / Ambient temperature

2: 80 percent / 6 N HCl / 24 h / Heating

3: 85 percent / hydrogen / platinum oxide / ethanol; H₂O / 24 h / 60 °C / 3102.9 Torr

With hydrogenchloride; hydrogen; N,N-Dimethylcarbamoyl chloride; platinum(IV) oxide; In ethanol; dichloromethane; water;
DOI:10.1021/jo00289a058