13b,13c-di(4-methoxyphenyl)-1,2,3,4,8,9,10,11-octa-methyl-5,7,12,13b,13c,14-hexahydro-5a,6a,12a,13a-tetraazabenzo[5,6]azuleno[2,1,8-ija]benzo[f]azulene-6,13-dione

Base Information

• Chemical Name: 13b,13c-di(4-methoxyphenyl)-1,2,3,4,8,9,10,11-octa-methyl-5,7,12,13b,13c,14-hexahydro-5a,6a,12a,13a-tetraazabenzo[5,6]azuleno[2,1,8-ija]benzo[f]azulene-6,13-dione
• CAS No.: 1000292-81-8
• Molecular Formula: C₄₂H₄₆N₄O₄
• Molecular Weight: 670.852
• Mol file: 1000292-81-8.mol

Synonyms:13b,13c-di(4-methoxyphenyl)-1,2,3,4,8,9,10,11-octa-methyl-5,7,12,13b,13c,14-hexahydro-5a,6a,12a,13a-tetraazabenzo[5,6]azuleno[2,1,8-ija]benzo[f]azulene-6,13-dione

Chemical Property of 13b,13c-di(4-methoxyphenyl)-1,2,3,4,8,9,10,11-octa-methyl-5,7,12,13b,13c,14-hexahydro-5a,6a,12a,13a-tetraazabenzo[5,6]azuleno[2,1,8-ija]benzo[f]azulene-6,13-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 13b,13c-di(4-methoxyphenyl)-1,2,3,4,8,9,10,11-octa-methyl-5,7,12,13b,13c,14-hexahydro-5a,6a,12a,13a-tetraazabenzo[5,6]azuleno[2,1,8-ija]benzo[f]azulene-6,13-dione

There total 3 articles about 13b,13c-di(4-methoxyphenyl)-1,2,3,4,8,9,10,11-octa-methyl-5,7,12,13b,13c,14-hexahydro-5a,6a,12a,13a-tetraazabenzo[5,6]azuleno[2,1,8-ija]benzo[f]azulene-6,13-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

1,2-bis(chloromethyl)-4,5-dimethylbenzene (2362-16-5) + 3a,6a-bis(4-methoxyphenyl)-tetrahydroimidazo[4,5-d]imidazole-2,5-(1H,3H)-dione (663908-73-4) → 13b,13c-di(4-methoxyphenyl)-1,2,3,4,8,9,10,11-octa-methyl-5,7,12,13b,13c,14-hexahydro-5a,6a,12a,13a-tetraazabenzo[5,6]azuleno[2,1,8-ija]benzo[f]azulene-6,13-dione (1000292-81-8)

Guidance literature:

With potassium hydroxide; In dimethyl sulfoxide; at 120 ℃; for 4h;

DOI:10.1139/V07-115

Reference yield: 57.0%

1,2,3,4-Tetramethylbenzene (488-23-3) + 3a,6a-bis(4-methoxyphenyl)-tetrahydroimidazo[4,5-d]imidazole-2,5-(1H,3H)-dione (663908-73-4) → 13b,13c-di(4-methoxyphenyl)-1,2,3,4,8,9,10,11-octa-methyl-5,7,12,13b,13c,14-hexahydro-5a,6a,12a,13a-tetraazabenzo[5,6]azuleno[2,1,8-ija]benzo[f]azulene-6,13-dione (1000292-81-8)

Guidance literature:

3a,6a-bis(4-methoxyphenyl)-tetrahydroimidazo[4,5-d]imidazole-2,5-(1H,3H)-dione; With potassium hydroxide; In dimethyl sulfoxide; at 120 ℃; for 0.5h;

1,2,3,4-Tetramethylbenzene; In dimethyl sulfoxide; at 120 ℃; for 4h; Further stages.;

DOI:10.3184/030823407X245606

Reference yield:

1,2-bis(4-methoxyphenyl)-1,2-ethanedione (1226-42-2) → 13b,13c-di(4-methoxyphenyl)-1,2,3,4,8,9,10,11-octa-methyl-5,7,12,13b,13c,14-hexahydro-5a,6a,12a,13a-tetraazabenzo[5,6]azuleno[2,1,8-ija]benzo[f]azulene-6,13-dione (1000292-81-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 81 percent / TFA / toluene / Heating

2.1: KOH / dimethylsulfoxide / 0.5 h / 120 °C

2.2: 57 percent / dimethylsulfoxide / 4 h / 120 °C

With potassium hydroxide; trifluoroacetic acid; In dimethyl sulfoxide; toluene;

DOI:10.3184/030823407X245606

upstream raw materials:

1,2,3,4-Tetramethylbenzene

3a,6a-bis(4-methoxyphenyl)-tetrahydroimidazo[4,5-d]imidazole-2,5-(1H,3H)-dione

1,2-bis(chloromethyl)-4,5-dimethylbenzene

1,2-bis(4-methoxyphenyl)-1,2-ethanedione

Downstream raw materials:

13b,13c-di(4-hydroxyphenyl)-1,2,3,4,8,9,10,11-octa-methyl-5,7,12,13b,13c,14-hexahydro-5a,6a,12a,13a-tetraazabenzo[5,6]azuleno[2,1,8-ija]benzo[f]azulene-6,13-dione