Technology Process of 4-CYANO-3,5-DIFLUOROPHENYL 4-PENTYL-BENZOATE
There total 6 articles about 4-CYANO-3,5-DIFLUOROPHENYL 4-PENTYL-BENZOATE which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
4-pyrrolidin-1-ylpyridine; dicyclohexyl-carbodiimide;
In
dichloromethane;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 99 percent / n-butyllithium / hexane; tetrahydrofuran / 2.5 h / -78 °C
2: oxalyl chloride, DMF / benzene / Ambient temperature
3: 81 percent / 35percent ammonia / bis-(2-methoxy-ethyl) ether / Ambient temperature
4: 95 percent / thionyl chloride / dimethylformamide / Ambient temperature
5: 94 percent / aluminum chloride, sodium chloride / hexane; tetrahydrofuran / 1 h / 180 °C
6: 33 percent / dicyclohexylcarbodiimide, 4-(N-pyrrolidino)pyridine / CH2Cl2 / Ambient temperature
With
ammonium hydroxide; n-butyllithium; aluminium trichloride; thionyl chloride; oxalyl dichloride; 4-pyrrolidin-1-ylpyridine; N,N-dimethyl-formamide; dicyclohexyl-carbodiimide; sodium chloride;
In
tetrahydrofuran; hexane; dichloromethane; diethylene glycol dimethyl ether; N,N-dimethyl-formamide; benzene;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 94 percent / aluminum chloride, sodium chloride / hexane; tetrahydrofuran / 1 h / 180 °C
2: 33 percent / dicyclohexylcarbodiimide, 4-(N-pyrrolidino)pyridine / CH2Cl2 / Ambient temperature
With
aluminium trichloride; 4-pyrrolidin-1-ylpyridine; dicyclohexyl-carbodiimide; sodium chloride;
In
tetrahydrofuran; hexane; dichloromethane;
